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Prevalence of extended-spectrum betalactamase producing–Enterobacteriaceae (ESBL-E) carriage on admission at Geneva University Hospitals (HUG)

  • 1,
  • 2,
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  • 1 and
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Antimicrobial Resistance and Infection Control20154(Suppl 1):P120

https://doi.org/10.1186/2047-2994-4-S1-P120

Published: 16 June 2015

Keywords

  • Pneumonia
  • Early Detection
  • Control Measure
  • European Study
  • Recent History

Introduction

The increasing prevalence of ESBL-E in the community is a cause of concern for hospitals. Early detection of ESBL-E carriers on admission could allow timely implementation of control measures or appropriate selection of antimicrobials.

Objectives

To describe the current prevalence of ESBL-E rates upon admission to 4 different services at HUG, in the context of a multicenter European study (R-Gnosis).

Methods

Patients admitted to 4 different services were screened by rectal swabs on admission. From January 2014 through January 2015, patients admitted to 4 wards, including: Ortho1 (sport traumatology), Ortho 2 (septic); Geriatrics (2 wards) and patients undergoing elective colorectal surgery (ECS) were screened from April 2013-October 2014.

Results

Overall, from 2394 admitted patients, 2136 were screened on admission (89.2%). Median age was 67.3 years (SD±20.9); 51.6% were male. Only 92/2136 (4.3%) had a previously known status of ESBL carriage. A total of 226/2136 (10.6%) patients were found to be ESBL-E carriers: E. coli (n=166; 73.4%); K. pneumoniae (n=26; 11.5%) and other Enterobacteriaceae (n=34; 15.0%). Among K. pneumonia carriers on admission, 24/26 (92.3%), had a previous hospitalization less than 12 months before admission screening and 21/26 (80.8%) had the previous hospitalization within 3 months only. ESBL-E carriage was 83/981 (8.4%) and 61/430 (14.2%) for Ortho 1 and 2 respectively; Geriatrics, 42/371 (11.3%); and ECS, 41/354 (11.6%).

Conclusion

Overall 10.6% of patients screened were ESBL-E carriers upon admission at HUG, mostly due to ESBL-producing E. coli. Patients admitted to septic orthopedics, geriatrics and ECS had a higher prevalence on admission. The majority of ESBL- Klebsiella pneumonia carriers had a recent history of hospitalization.

Disclosure of interest

None declared.

Authors’ Affiliations

(1)
Infection Control Programme, Geneva University Hospitals, Geneva, Switzerland
(2)
Bacteriology Laboratory, Geneva University Hospitals, Geneva, Switzerland
(3)
Geriatrics, Internal Medicine and Rehabilitation Service, Geneva University Hospitals, Geneva, Switzerland
(4)
Visceral Surgery Service, Geneva University Hospitals, Geneva, Switzerland
(5)
Anesthesiology Service, Geneva University Hospitals, Geneva, Switzerland
(6)
R-Gnosis WP5 Leader, Charité-University Hospital, Berlin, Germany
(7)
R-Gnosis WP4 Leader, Sourasky Medical Center, Tel-Aviv, Israel

Copyright

© Fankhauser et al; licensee BioMed Central Ltd. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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