Volume 4 Supplement 1

Antimicrobial Resistance and Infection Control: Abstracts from the 3rd International Conference on Prevention and Infection Control (ICPIC 2015)

Open Access

Bloodstream infections caused by multidrug-resistant non-fermentative bacilli in southern of Poland in 2013

  • A Chmielarczyk1,
  • M Pomorska-Wesołowska2,
  • M Pobiega1,
  • G Ziółkowski3,
  • D Romaniszyn1 and
  • J Wojkowska-Mach1
Antimicrobial Resistance and Infection Control20154(Suppl 1):P138

https://doi.org/10.1186/2047-2994-4-S1-P138

Published: 16 June 2015

Introduction

Modern medicine requires a clear and explicit criteria to describe the phenomena of public health; and one of the major problems of public health is drug resistance of microorganisms.

Objectives

The aim of this study was to analyze how big epidemiological problem are highly-resistant – multidrug-resistant (MDR) and extensively-drug resistant (XDR) non-fermentative bacilli isolated from bloodstream infections (BSI) in southern Poland.

Methods

The study comprised consecutive, non-repetitive non-fermentative bacilli (NFB) isolates received by the Chair of Microbiology UJCM with collaborative 2 laboratories in 2013 from BSI of hospitalized (12 hospitals) throughout south of Poland (Malopolska and Silesia).

Studied strains from BSI were belonging to groups: ACI (Acinetobacter baumannii n=21, Acinetobacter lwoffii n=1, Acinetobacter ursingi n=1), PAR (Pseudomonas aeruginosa n=12), and others (Stenotrophomonas malthophilia n=10, Achromobacter denitrificans n=5, Comamonas testosterone n=1, Ochrobactrum anthropi n=1).

Antimicrobial susceptibility was assessed according to current EUCAST guidelines. Different patterns of resistance were defined according to Magiorakos (2012) as: MDR strains or XDR.

Results

NFB strains occurred with different frequencies, the highest prevalence was associated with ACI: 1.3%.

More than 75% of ACI strains were resistant to 14 out of 16 antimicrobials, among ACI also found the highest share of XDR: 95.7%. The most of these isolates were resistant to all antibiotics with the exception of colistin: MIC50 for colistin was 1.

In the group of PAR isolates 91.7% were XDR, MIC50 for colistin was 1.

DiversiLab typing demonstrated the presence of two dominant ACI clones. Clone 1 and clone 2 , both are classified as the European clone 2 (EUII).

Conclusion

The presented data indicate a high potential therapeutic problems related to the large resistance of ACI isolates. The used stratification of drug resistance (MDRO/XDR/PDR) may become an important tool for the assessment of public health and microbiological hazards at different levels. (supported by DEC-2012/05/B/NZ7/02880).

Disclosure of interest

None declared.

Authors’ Affiliations

(1)
Jagiellonian University Medical School
(2)
Department of Microbiology, Analytical and Microbiological Laboratory, Korlab Nzoz
(3)
Higher School of Medicine in Sosnowiec

Copyright

© Chmielarczyk et al; licensee BioMed Central Ltd. 2015

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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