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Volume 4 Supplement 1

Antimicrobial Resistance and Infection Control: Abstracts from the 3rd International Conference on Prevention and Infection Control (ICPIC 2015)

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Health care associated Clostridium difficile infections in University Hospital Trnava during last five years (2010 – 2014)

Antimicrobial Resistance and Infection Control volume 4, Article number: P24 (2015) Cite this article

Introduction

In Slovakia, mandatory surveillance of Clostridium difficile infection (CDI) have been established due to electronically national Epidemiological information systems (EPIS) long time ago, but compliance to surveillance are low.

Objectives

The aim of this hospital-based study was to assess real prevalence and outcome of CDI in University Hospital Trnava, Slovakia during years 2010-2014.

Methods

We analysed all patients with laboratory confirmed CDI (RIDA®QUICK Clostridium difficile Toxin A/B immunochromatographic rapid assay, R-Biopharm) in University Hospital Trnava (618-bed; approx. 25 000 patients per year) from laboratory information system and medical records.

Results

During five years period were identified 317 CDI with declining trend in recent years for 10 000 admission. Health care associated CDI (HA-CDI) accounted for 75,7% (240). The mean age of patients was 72,8 ± 15 years (range 15-96) and 60,3% (191) were women. The most frequently antibiotics used before onset CDI were quinolones (25,9%) for the treatment of respiration or urinary tract infection. Overall recurrence of CDI was observed within 3 months after the first episode in 6,9% (22) of cases. Total hospital mortality rate was 13,9% (44) and hospital mortality associated with CDI only 1,9% (6).

Conclusion

These results show high prevalence HA-CDI in our hospital and emphasizing the importance of implementing better infection control practice in order to prevent further spread. To date no data about specific ribotype of Clostridium difficile and about prevalence in long-term care facility are available in Slovakia.

Disclosure of interest

None declared.

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Authors and Affiliations

  1. Department of Public Health, Trnava University, Trnava, Slovakia

    A Streharova & M Garabasova

  2. Department of Laboratory Medicine, School of Health Sciences and Social Work, Trnava University, Trnava, Slovakia

    JS Brnova

  3. Laboratory of Molecular Microbiology, St. Elisabeth University, Bratislava, Slovakia

    JS Brnova

Authors
  1. A Streharova
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  2. M Garabasova
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  3. JS Brnova
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This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Streharova, A., Garabasova, M. & Brnova, J. Health care associated Clostridium difficile infections in University Hospital Trnava during last five years (2010 – 2014). Antimicrob Resist Infect Control 4 (Suppl 1), P24 (2015). https://doi.org/10.1186/2047-2994-4-S1-P24

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  • DOI: https://doi.org/10.1186/2047-2994-4-S1-P24

Keywords

Antimicrobial Resistance & Infection Control

ISSN: 2047-2994

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