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Table 4 Resistance profile of isolates tested against 6 major classes of antibiotics with different mode of action

From: Community acquired multi-drug resistant clinical isolates of Escherichia coli in a tertiary care center of Nepal

Mode of action

Antibiotic classes

No. of isolates resistant to at least one agent of antibiotic classes (%)

Inhibition of cell wall synthesis

Beta-lactams

200 (100)

Inhibition of protein synthesis

Aminoglycosides

56 (28)

Inhibition of DNA replication

Fluoroquinolones

82 (41)

 

Chloramphenicol

34 (17)

Inhibition of folic acid metabolism

Cotrimoxazole

118(59)

Damaging of cytoplasmic membrane

Polymyxins (colistin)

0 (0)