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Table 4 Resistance profile of isolates tested against 6 major classes of antibiotics with different mode of action

From: Community acquired multi-drug resistant clinical isolates of Escherichia coli in a tertiary care center of Nepal

Mode of action Antibiotic classes No. of isolates resistant to at least one agent of antibiotic classes (%)
Inhibition of cell wall synthesis Beta-lactams 200 (100)
Inhibition of protein synthesis Aminoglycosides 56 (28)
Inhibition of DNA replication Fluoroquinolones 82 (41)
  Chloramphenicol 34 (17)
Inhibition of folic acid metabolism Cotrimoxazole 118(59)
Damaging of cytoplasmic membrane Polymyxins (colistin) 0 (0)