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Table 2 Results of TEWL measurements. Differences between agents (safety population, n = 22)

From: Safety and tolerability of virucidal hand rubs: a randomized, double-blind, cross-over trial with healthy volunteers

Difference to agent
  P2 P3 R
Agent Differ-ence 95 %-CI P Difference 95 %-CI P Difference 95 %-CI P
 P1 6.16 2.54–9.79 0.0013 6.14 2.38–9.89 0.002 −1.54 −5.33 - 2.26 0.42
 P2 - - - −0.03 −3.69 - 3.64 0.99 −7.70 −11.45 - −2.96 0.0001
 P3 - - - - - - −7.67 −11.45 - − 3.90 0.0002
  1. P1 = Ethanol (100 %) 45 g, 1-Propanol (Ph.Eur.) 18 g (Softa-Man® acute, B. Braun Melsungen AG), P2 = Ethanol (99 %) 95 g (Sterillium® virugard, Bode Chemie Hamburg GmbH), and, P3 = Ethanol (96 %) 57,6 g, 1-Propanol (Ph.Eur.) 10 g (Manorapid® Synergy, Antiseptica GmbH, R (reference product) = Ethanol (100 %) 45 g, 1-Propanol (Ph.Eur.) 18 g (Softa-Man® pure, B. Braun Melsungen AG)