Drug susceptibility patterns of the Mycobacterium tuberculosis isolated from previously treated and new cases of pulmonary tuberculosis at German-Nepal tuberculosis project laboratory, Kathmandu, Nepal

Table 2 Drug susceptibility patterns of Mycobacterium tuberculosis isolated from different groups of previously treated patients

Susceptibility patterns	Total cases (N = 93) n (%)	Relapse (N = 55) n (%)	Treatment failure (N = 14) n (%)	Return after default (N = 8) n (%)	Follow up (N = 5) n (%)	Chronic (N = 11) n (%)
Any drug resistance	33 (35.5)	18 (32.7)	4 (28.6)	4 (50)	1 (20)	6 (54.6)
Any isoniazid resistance	28 (30.1)	16 (29.1)	2 (14.3)	3 (3.8)	1 (20)	6 (54.6)
Any rifampicin resistance	20 (21.5)	11 (20)	3 (21.4)	2 (25)	1 (20)	3 (27.3)
Mono isoniazid resistance	2 (2.2)	1 (1.8)	0	0	0	1 (9.1)
Mono rifampicin resistance	1 (1.1)	0	1 (7.1)	0	0	0
MDR-TB	18 (19.4)	11 (20)	2 (14.3)	1 (12.5)	1 (20)	3 (27.3)
Poly-resistant TB (resistant to more than one drug, but not MDR-TB)	9 (9.7)	4 (7.3)	0	4 (50)	0	2 (18.2)

Note: Relapse cases are the patients who become symptomatic after completion of the treatment, treatment failure cases are the patients who remain smear positive or culture positive even after 5 or more months of start of anti-tubercular therapy, default cases are the patients whose treatment is halted for at least two consecutive months, follow up cases are the patients who are called in follow up even after successful completion of anti-tubercular therapy, chronic cases are the patients who have received repeated incomplete treatment and who still have active tuberculosis that is considered to be incurable [6]

ISSN: 2047-2994