Table 3 The drug susceptibility patterns of M. tuberculosis isolated in different studies conducted in Nepal during different periods of time
National survey 1996–1997 [21] | National survey 1998–1999 [21] | National survey 2001–2002 [21] | Rijal et al. 2003–2004 [16] | Subba et al. 2005–2006 [17] | Pradhan et al. 2006–2007 [18] | National survey 2006–2007 [21] | Finding of our study 2013 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
New cases | Previously treated cases | New cases | Previously treated cases | New cases | Previously treated cases | New cases | Previously treated cases | New cases | Previously treated cases | New cases | Previously treated cases | New cases | Previously treated cases | New cases | Previously treated cases | |
Any drug resistance | 9.8 % | 0 | 13.2 % | 28.6 % | 11.0 % | 40.9 % | 36.8 % | 75.2 % | 64.5 % | 74.8 % | 46.5 % | 67.2 % | 4.7 % | 25.3 % | 21.4 % | 35.5 % |
Mono-drug resistance | 5.7 % | 0 | 7.6 % | 11.6 % | 7.0 % | 13.0 % | 23.7 % | 32.3 % | 20 % | 23.6 % | 24.3 % | 25.9 % | 9.1 % | 6.1 % | 14.3 % | 6.5 % |
Multidrug resistance | 1.1 % | 0 | 3.7 % | 12.5 % | 1.32 % | 20.5 % | 2.6 % | 19.3 % | 22.2 % | 37.2 % | 4.2 % | 15.5 % | 2.9 % | 11.7 % | 7.1 % | 19.4 % |
Resistance to all 4 first line drugs | 0 | 0 | 1.8 % | 9.8 % | 0.8 % | 9.4 % | 2.6 % | 11.8 % | 6.7 % | 18.8 % | 0 | 6.9 % | 1.8 % | 6.8 % | 4.8 % | 15.1 % |