Parameter
|
Survived until 7 days after BSI
|
Died within 7 days after BSI
|
7-days Mortality
|
P-value
|
Survived/ discharged after BSI
|
Died in-hospital after BSI
|
In-hospital Mortality
|
P-value
|
---|
Number (%)
|
Number (%)
|
Number (%)
|
Number (%)
|
---|
Patients
|
1.690 (100 %)
|
161 (100 %)
|
8.7 %
| |
1485 (100 %)
|
366 (100 %)
|
19.8 %
| |
K. pneumoniae
|
319 (18.9 %)
|
33 (20.5 %)
|
9.4 %
|
0.616
|
264 (17.8 %)
|
88 (24.0 %)
|
25.0 %
|
0.006
|
E. coli
|
1371 (81.1 %)
|
128 (79.5 %)
|
8.5 %
|
1221 (82.2 %)
|
278 (76.0 %)
|
18.5 %
|
ESBL-positive
|
219 (13.0 %)
|
25 (15.5 %)
|
10.2 %
|
0.357
|
183 (12.3 %)
|
61 (16.7 %)
|
25.0 %
|
0.028
|
Hospital mortality
|
205 (12.1 %)
|
161 (100.0 %)
|
44.0 %
|
<0.001
|
-
|
366 (100.0 %)
|
100.0 %
|
n.a.
|
Polymicrobial
|
198 (11.7 %)
|
27 (16.8 %)
|
12.0 %
|
0.061*
|
160 (10.8 %)
|
65 (17.8 %)
|
28.9 %
|
<0.001*
|
Age (years)a
|
65 (52–73)a
|
67 (57–76)a
|
n.a.
|
0.019*
|
65 (52–73)a
|
66 (54–74)a
|
n.a.
|
0.134*
|
Male
|
929 (55.0 %)
|
93 (57.8 %)
|
9.1 %
|
0.496
|
799 (53.8 %)
|
223 (60.9 %)
|
21.8 %
|
0.014
|
Hospital onset
|
746 (44.1 %)
|
84 (52.2 %)
|
10.1 %
|
0.050*
|
612 (41.2 %)
|
218 (59.6 %)
|
26.3 %
|
<0.001*
|
ICU stay
|
1.072 (63.4 %)
|
125 (77.6 %)
|
10.4 %
|
<0.001*
|
896 (60.3 %)
|
301 (82.2 %)
|
25.1 %
|
<0.001*
|
Charlson comorbidity indexa
|
5 (3–8)a
|
8 (6–10)a
|
n.a.
|
<0.001
|
5 (3–8)a
|
8 (6–10)a
|
n.a.
|
<0.001
|
Heart disease
|
275 (16.3 %)
|
47 (29.2 %)
|
14.6 %
|
<0.001*
|
215 (14.5 %)
|
107 (29.2 %)
|
33.2 %
|
<0.001*
|
Cerebrovascular disease
|
243 (14.4 %)
|
31 (19.3 %)
|
11.3 %
|
0.096*
|
202 (13.6 %)
|
72 (19.7 %)
|
26.3 %
|
0.003*
|
Neurologic disease
|
123 (7.3 %)
|
11 (6.8 %)
|
8.2 %
|
0.835
|
112 (7.5 %)
|
22 (6.0 %)
|
16.4 %
|
0.311
|
Lung disease
|
218 (12.9 %)
|
24 (14.9 %)
|
9.9 %
|
0.470
|
181 (12.2 %)
|
61 (16.7 %)
|
25.2 %
|
0.023
|
Gastrointestinal disease
|
53 (3.1 %)
|
12 (7.5 %)
|
18.5 %
|
0.004*
|
36 (2.4 %)
|
29 (7.9 %)
|
44.6 %
|
<0.001*
|
Rheumatic disease
|
50 (3.0 %)
|
2 (1.2 %)
|
3.8 %
|
0.208
|
44 (3.0 %)
|
8 (2.2 %)
|
15.4 %
|
0.420
|
Liver disease
|
258 (15.3 %)
|
53 (32.9 %)
|
17.0 %
|
<0.001*
|
180 (12.1 %)
|
131 (35.8 %)
|
42.1 %
|
<0.001*
|
Diabetes
|
422 (25.0 %)
|
48 (29.8 %)
|
10.2 %
|
0.177
|
366 (24.6 %)
|
104 (28.4 %)
|
22.1 %
|
0.138
|
Renal disease
|
711 (42.1 %)
|
115 (71.4 %)
|
13.9 %
|
<0.001*
|
565 (38.0 %)
|
261 (71.3 %)
|
31.6 %
|
<0.001*
|
Cancer/immunological disease
|
672 (39.8 %)
|
75 (46.6 %)
|
10.0 %
|
0.092*
|
571 (38.5 %)
|
176 (48.1 %)
|
23.6 %
|
0.001*
|
-
BSI bloodstream infection, LOS length of stay, N.a. not applicable
- * Included in the multivariable Cox-proportional hazard regression
-
a Continuous parameter displayed as median (interquartile range)
-
P-values <0.05 were considered statistically significant