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Table 1 Criteria for inclusion as definite, probably, possible, and unlikely cases of daptomycin-induced eosinophilic pneumonia [1, 2]

From: Daptomycin-induced eosinophilic pneumonia - a systematic review

Definite Probable Possible Unlikely
Concurrent exposure to daptomycin Concurrent exposure to daptomycin Concurrent exposure to daptomycin All other cases that did not meet criteria
Dyspnea with increased oxygen requirement or requiring mechanical ventilation Dyspnea with increased oxygen requirement or requiring mechanical ventilation New infiltrates on CXR or CT  
New infiltrates on CXR or CT New infiltrates on chest x-ray or CT Clinical improvement following daptomycin withdrawal OR the patient died  
BAL with > 25% eosinophils BAL with ≤ 25% eosinophils OR peripheral eosinophilia   
Clinical improvement following daptomycin withdrawal Clinical improvement following daptomycin withdrawal   
Fever    
  1. Adapted from references 1 and 2
  2. Abbreviation: BAL bronchoalveolar lavage; CT computed tomography; CXR chest x-ray