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Table 2 Univariate analysis of risk factors for organ-space surgical site infection in colon and rectal surgery

From: Risk factors and outcomes of organ-space surgical site infections after elective colon and rectal surgery

  Colon Rectum
Risk factor No OS-SSI (n = 2318) OS-SSI (n = 200) p- value No OS-SSI (n = 1043) OS-SSI (n = 136) p- value
Age, median (IQR) years 70 (61–79) 73 (63–79) 0.3 68 (60–76) 66.5 (58–74) 0.07
Age ≥ 65 years, (%) 67.6 72 0.2 61.5 58.8 0.5
Male sex, (%) 58.4 70 0.001 65.4 80.9 <0.001
ASA ≥ III, (%) 41.9 45.5 0.3 36.1 41.2 0.25
Correct IV antibiotic prophylaxis, (%) 84.3 81.5 0.3 81.4 83.8 0.5
Duration of operation ≥ p75tha, (%) 37.5 39 0.7 41.2 54.4 0.003
Laparoscopy, (%) 61.6 44 <0.001 66.3 64.7 0.7
NNIS ≥ 1, (%) 35.5 43 0.03 32.7 41.2 0.05
Neoplasia, (%) 93.6 93 0.7 97.2 94.9 0.13
Inflammatory bowel disease, (%) 2.9 4 0.38 1.1 2.9 0.1
Chemotherapy, (%) 3.1 3.5 0.7 45.1 45.2 1
Radiotherapy, (%) 1.2 2.5 0.18 46 47.4 0.7
Oral antibiotic prophylaxis, (%) 43.7 33 0.004 43.3 26.5 <0.001
Mechanical bowel preparation, (%) 71.4 67.2 0.2 89.1 90.4 0.6
Ostomy, (%) 7.3 20 <0.001 63.8 65.2 0.7
  1. No OS-SSI no organ-space surgical site infections (include patients with incisional SSI and patients without SSI), OS-SSI organ-space SSI, IQR interquartile range, ASA American Society of Anesthesiologists physical status classification, IV intravenous, NNIS National Nosocomial Infections Surveillance Risk Index.
  2. aGreater than 75th percentile for the duration of surgery (180 min, 3 h)