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Table 2 Summary MIC data for nine antimicrobials against Thai C. difficile isolates by toxin gene profile

From: Antimicrobial susceptibility of Clostridium difficile isolated in Thailand

Antimicrobiala Toxigenic isolates (n = 39) A−B− isolates (n = 66) A+B+ isolates (n = 27) A−B+ isolates (n = 12)
MIC Range MIC50/MIC90 MIC Range MIC50/MIC90 MIC Range MIC50/MIC90 MIC Range MIC50/MIC90
FDX 0.008–0.25 0.06/0.25 0.004–0.25 0.06/0.25 0.015–0.25 0.12/0.25 0.008–0.06 0.03/0.06
VAN 0.25–2 1/2 0.06–2 1/1 0.25–2 1/2 0.5–2 1/1
MTZ 0.015–0.25 0.25/0.25 0.015–0.5 0.25/0.5 0.015–0.25 0.25/0.25 0.015–0.25 0.12/0.25
RFX 0.015–>16 0.03/>16 0.008–>16 0.015/0.03 0.015–0.03 0.015/0.03 0.015–>16 >16/>16
CLI 0.015–>32 8/>32 0.03–>32 8/>32 0.015–16 8/16 0.015–>32 >32/>32
ERY 0.5–>256 2/>256 0.12–>256 2/>256 0.5–2 2/2 1–>256 >256/>256
AMC 0.03–1 0.5/1 0.03–2 0.5/1 0.03–1 0.5/1 0.03–1 0.5/1
MXF 0.12–>32 2/32 0.12–>32 2/16 0.12–4 2/2 0.25–32 16/32
MEM 0.25–4 2/4 0.25–4 2/4 0.5–4 2/4 0.25–4 4/4
  1. a FDX fidaxomicin, VAN vancomycin, MTZ metronidazole, RFX rifaximin, CLI clindamycin, ERY erythromycin, AMC amoxicillin/clavulanate, MXF moxifloxacin, MEM meropenem. All values are shown in mg/L