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Table 2 Three-hours bactericidal effects of the modified WHO-formulation II and TPH 5766 as compared to that of the reference hand rub for pre-surgical hand antisepsis according to EN 12791

From: Influence of glycerol and an alternative humectant on the immediate and 3-hours bactericidal efficacies of two isopropanol-based antiseptics in laboratory experiments in vivo according to EN 12791

Formulation duration of application
(n × 3 ml)
Mean (n = 20)
log10 pre-value
Mean (n = 20)
log10 reduction
p-value fordifference to reference
Reference 3 min 4.47 ± 0.55 2.03 ± 0.93  
WHO II-modified 3 min 4.30 ± 0.59 1.41 ± 1.32 0.014a
WHO II-modified 5 min 4.51 ± 0.58 1.74 ± 1.15 0.081
TPH 5766 3 min 4.41 ± 0.65 2.08 ± 1.24 0.847
TPH 5766 5 min 4.32 ± 0.65 2.13 ± 1.17 0.651
  1. P < 0.05, two-sided (ANOVA, linear contrasts)
  2. asignificantly less efficacious than the reference