Formulation | duration of application (n × 3 ml) | Mean (n = 20) log10 pre-value | Mean (n = 20) log10 reduction | p-value fordifference to reference |
---|---|---|---|---|
Reference | 3 min | 4.47 ± 0.55 | 2.03 ± 0.93 | |
WHO II-modified | 3 min | 4.30 ± 0.59 | 1.41 ± 1.32 | 0.014a |
WHO II-modified | 5 min | 4.51 ± 0.58 | 1.74 ± 1.15 | 0.081 |
TPH 5766 | 3 min | 4.41 ± 0.65 | 2.08 ± 1.24 | 0.847 |
TPH 5766 | 5 min | 4.32 ± 0.65 | 2.13 ± 1.17 | 0.651 |