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Table 2 Antibiotic susceptibility of MSSA and MRSA following sub-lethal exposure to 405 nm light

From: Assessment of the potential for resistance to antimicrobial violet-blue light in Staphylococcus aureus

Antibiotic Conc (μg) Mean Diameter of Zone of Inhibition of MSSA (mm) Mean Diameter of Zone of Inhibition of MRSA (mm)
0 5 10 15 0 5 10 15
Chloramphenicol 25a 21 ± 1.5 21 ± 0.8 21 ± 1.2 21 ± 0.8 24 ± 1.0 24 ± 1.1 23 ± 1.4 23 ± 1.1
Ciprofloxacin 5 22 ± 1.2 21 ± 0.5 22 ± 0.7 22 ± 1.3 26 ± 0.6 26 ± 0.4 26 ± 1.0 26 ± 1.1
Erythromycin 5a 21 ± 0.6 21 ± 0.6 22 ± 0.8 21 ± 0.4 23 ± 1.0 22 ± 0.8 23 ± 1.0 23 ± 1.2
Fusidic Acid 10 30 ± 0.0 30 ± 0.8 32 ± 1.0* 31 ± 1.8 31 ± 0.6 30 ± 0.5 30 ± 0.7 30 ± 0.9
Gentamicin 10 21 ± 0.6 21 ± 0.5 21 ± 0.5 20 ± 0.5 21 ± 0.6 21 ± 0.5 22 ± 1.3 23 ± 0.6*
Mupirocin 5a 28 ± 0.6 26 ± 0.5* 28 ± 1.4 28 ± 1.1 26 ± 0.6 27 ± 1.1 26 ± 1.2 26 ± 1.3
Oxacillin 5b 30 ± 0.0 29 ± 0.9 30 ± 0.6 30 ± 0.9 0 ± 0.0 0 ± 0.0 0 ± 0.0 0 ± 0.0
Rifampicin 5 32 ± 1.0 32 ± 0.7 33 ± 1.8 34 ± 0.6* 31 ± 0.6 30 ± 0.7 31 ± 1.0 31 ± 0.9
Tetracycline 25a 28 ± 1.2 28 ± 1.0 28 ± 1.4 29 ± 1.3 27 ± 1.0 27 ± 0.7 27 ± 1.0 26 ± 0.9
Vancomycin 5b 15 ± 0.0 14 ± 0.7 15 ± 0.7 15 ± 0.5 14 ± 0.6 15 ± 0.6 15 ± 0.5 14 ± 0.5
  1. Antibiotic susceptibility of methicillin-sensitive Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA) after 5, 10 and 15 sub-lethal exposures compared to equivalent non-sub-lethally exposed controls (0). Susceptibility was measured using Disc Diffusion Method
  2. *indicates diameters of zones of inhibition that was significantly different to the equivalent non-sub-lethally exposed control (P ≤ 0.05). Each data point is a mean value ± SD (n ≥ 3)
  3. aDisc concentration is lower than that recommended by EUCAST
  4. bNo disc concentration recommended by EUCAST