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Table 1 Characteristics of E. coli ST131 isolates by fimH subtyping

From: Prevalence and characteristics of ST131 clone among unselected clinical Escherichia coli in a Chinese university hospital

Characteristics   ST131 subclones, number of isolates (%) P a
Total H30Rx H30 non-Rx H41 H41 vs H30 non -Rx H41 vs H30-Rx H30 Rx vs H30 non-Rx
N = 83 (%) n = 13 n = 40 n = 30    
PCR O type
 O25b 55(66.3%) 12(92.3%) 40(100%) 3(10.0%) < 0.001 < 0.001  
 O16 28(33.7%) 1(7.7%) 0 27(90.0%)    
Antimicrobial resistance
 ATM 30(36.1%) 12(92.3%) 11(27.5%) 7(23.3%)   < 0.001 < 0.001
 CAZ 22(26.5%) 10(76.9%) 5(12.5%) 7(23.3%)   0.002 < 0.001
 CTX 59(71.1%) 12(92.3%) 28(70%) 19(63.3%)    
 FEP 26(31.3%) 11(84.6%) 10(25.0%) 5(16.7%)   < 0.001 < 0.001
 TZP 1(1.2%) 0 0 1(3.3%)    
 CIP 58(69.9%) 13(100%) 40(100%) 5(16.7%) < 0.001 < 0.001  
 LEV 58(69.9%) 13(100%) 40(100%) 5(16.7%) < 0.001 < 0.001  
 AMK 7(8.4%) 3(23.1%) 1(2.50%) 3(10.0%)    0.042
 SXT 56(67.5%) 10(76.9%) 24(60.0%) 22(73.3%)    
bla CTX-M type
 CTX-M-14 37(44.6%) 0 22(55.0%) 15(50.0%)   0.001 < 0.001
 CTX-M-15 22(26.5%) 12(92.3%) 7(17.5%) 3(10.0%)   < 0.001 < 0.001
 CTX-M-14,15 2(2.40%) 0 2(5.0%) 0    
 CTX-M-123 1(1.2%) 0 0 1(3.3%)    
 No ESBLb 21(25.3%) 1(7.7%) 11(27.5%) 9(30.0%)    
FQR genesc
 5 gyrA, parC and parE mutationsd 51(61.4%) 13(100%) 35(87.5%) 3(10.0%) < 0.001 < 0.001  
aac(6′)-Ib-cr 14(16.9%) 10(76.9%) 0 4(13.3%) 0.012 < 0.001 < 0.001
qnr 4(4.8%) 0 2(5.0%) 2(6.70%)    
Adhesins
papAH 22 (26.5%) 12(92.3%) 6 (15.0%) 4(13.3%)   < 0.001 < 0.001
papC 23 (27.7%) 13(100%) 6 (15.0%) 4(13.3%)   < 0.001 < 0.001
papEF 22 (26.5%) 12(92.3%) 7(17.5%) 3(10.0%)   < 0.001 < 0.001
papG allele I 0 0 0 0    
papG allele II 21 (25.3%) 12(92.3%) 6 (15.0%) 3(10.0%)   < 0.001 < 0.001
sfa/focDE 1 (1.2%) 0 1(2.50%) 0    
focG 0 0 0 0    
afa/draBC 7 (8.4%) 0 2(5.0%) 5(16.7%)    
fimH 82 (98.8%) 13(100%) 39(97.5%) 30(100%)    
gafD 0 0 0 0    
sfaS 7 (8.4%) 3(23.1%) 3(7.5%) 1(3.3%)    
Toxins
hlyA 14 (16.9%) 11(84.6%) 1(2.50%) 2(6.70%)   < 0.001 < 0.001
cnf1 10 (12.0%) 8(61.5%) 1(2.50%) 1(3.3%)   0.002 < 0.001
cdtB 0 0 0 0    
cvaC 3 (3.6%) 0 0 3(10.0%) 0.042   
Siderophores
fyuA 81 (97.6%) 13(100%) 38(95.0%) 30(100%)    
iutA 77 (92.8%) 13(100%) 38(95.0%) 26(86.7%)    
Capsules
kpsMT II 62 (74.7%) 9(69.2%) 33(82.5%) 20(66.7%)    
kpsMT III 0 0 0 0    
kpsMT K1 10 (12.0%) 2(15.4%) 5(12.5%) 3(10.0%)    
kpsMT K5 47 (56.6%) 11(84.6%) 29(72.5%) 7(23.3%) < 0.001 0.001  
Miscellaneous
nfaE 0 0 0 0    
rfc 0 0 0 0    
malX 76 (91.6%) 13(100%) 37(92.5%) 26(86.7%)    
traT 73 (88.0%) 13(100%) 32(80.0%.) 28(93.3%)    
 Virulence scorese 7 9 7 6   0.001 0.001
  1. a P values, by either χ2 or Fisher’s exact test or Mann-Whitney test, are shown where P < 0.05
  2. bESBL, CTX-M-type extended-spectrum-β-lactamase genes
  3. cFQR, fluoroquinolone resistance
  4. dGyrA S83 L, D87N, ParC S80I, E84V, and ParE I529L
  5. emedian number of virulence factors (range)