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Table 1 Patient characteristics and outcomes according to carbapenem-nonsusceptible A. baumannii-calcoaceticus complex status

From: Endemic carbapenem-nonsusceptible Acinetobacter baumannii-calcoaceticus complex in intensive care units of the national referral hospital in Jakarta, Indonesia

  Carbapenem-nonsusceptible A. baumannii-calcoaceticus complex positive on admission Carbapenem-nonsusceptible A. baumannii-calcoaceticus complex acquired during ICU stay Carbapenem-nonsusceptible A. baumannii-calcoaceticus complex negative p value
n = 69 (n = 89) n = 254
Age (years), median (IQR) 47 (33–60) 48 (35.3–57) 46 (32–58) 0.700
Gender (%)     0.535
 Male 35 (50.7) 42 (47.2) 137 (53.9)  
 Female 34 (49.3) 47 (52.8) 117 (46.1)  
Underlying diseases (%)
Cardiovascular     0.024
 Yes 9 (13.0) 3 (3.4) 13 (5.1)  
 No 60 (87.0) 86 (96.6) 241 (94.9)  
Cerebrovascular     0.001
 Yes 3 (4.3) 14 (15.7) 12 (4.7)  
 No 66 (95.7) 75 (84.3) 242 (95.3)  
Chronic kidney disease     0.915
 Yes 5 (7.2) 8 (9.0) 20 (7.9)  
 No 64 (92.8) 81 (91.0) 234 (92.1)  
Diabetes mellitus     0.334
 Yes 20 (29.0) 20 (22.5) 78 (30.7)  
 No 49 (71.0) 69 (77.5) 176 (69.3)  
Malignancy     0.740
 Yes 29 (42.0) 37 (41.6) 116 (45.7)  
 No 40 (58.0) 52 (58.4) 138 (54.3)  
Indication for ICU admission (%)     0.002
 Medical 32 (46.4) 38 (42.7) 70 (27.6)  
 Surgical 37 (53.6) 51 (57.3) 184 (72.4)  
Referral from (%)     0.900
 Other ward this hospital 38 (55.1) 48 (53.9) 136 (53.5)  
 Other hospital 14 (20.3) 14 (15.7) 49 (19.3)  
 Directly from Emergency Unit 17 (24.6) 27 (30.3) 69 (27.2)  
Antibiotic exposure (pre-ICU admission)
 Any antibiotic (%) 58 (84.1) 73 (82.0) 180 (70.9) 0.021
 Carbapenem (%) 24 (34.8) 22 (24.7) 33 (13.0) <0.01
SIRS Score, (%)     0.916
 Score ≥ 2 64 (92.8) 81 (91.0) 232 (91.3)  
 Score < 2 5 (7.2) 8 (9.0) 22 (8.7)  
qSOFA Score, (%)     0.089
 Score ≥ 2 51 (73.9) 78 (87.6) 205 (80.7)  
 Score < 2 18 (26.1) 11 (12.4) 49 (19.3)  
Procedures (during ICU admission)
 Mechanical ventilation (%) 63 (91.3) 88 (98.9) 220 (86.6) 0.004
 Mechanical ventilation (days) median(IQR) 5 (2–8) 8 (4–16) 3 (1–6)  
  ≥ 5 days (%) 36 (52.2) 63 (70.8) 83 (2.7) <0.01
  < 5 days (%) 33 (47.8) 26 (29.2) 171 (67.3)  
 Central venous catheter (%) 66 (95.7) 85 (95.5) 212 (83.5) <0.01
 Central venous catheter (days) median(IQR) 6 (3–9) 10 (5–17) 4 (2–7)  
  ≥ 5 days (%) 41 (59.4) 71 (79.8) 111 (3.7) <0.01
  < 5 days (%) 28 (40.6) 18 (20.2) 143 (56.3)  
 Urine catheter 69 (100) 89 (100) 254 (100) N/A
 Urine catheter (days) median (IQR) 6 (3–10) 10 (6–18) 5 (3–7)  
  ≥ 5 days (%) 26 (37.7) 13 (14.6) 122 (48.0) <0.01
  < 5 days (%) 43 (62.3) 76 (85.4) 132 (52.0)  
Antibiotic therapy (during ICU admission)
 Any antibiotic (%) 68 (98.6) 89 (100) 249 (98.0) 0.411
 Carbapenem (%) 42 (60.9) 62 (69.7) 95 (37.4) <0.01
Outcomes
 Length of stay (days), median (IQR) 5 (3–9) 11 (5–18) 4 (3–7) <0.01
 Death 22 (31.9) 38 (42.7) 59 (23.2) 0.002
  1. Abbreviations: ICU, Intensive Care Unit; IQR, Interquartile range; qSOFA, quick Sepsis-related Organ Failure Assessment; SIRS, Systemic Inflammatory Response Syndrome
  2. Significance was calculated using Oneway ANOVA and Pearson Chi Square
  3. A p-value less than 0.01 was considered statistically significant