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Table 1 Patient characteristics and outcomes according to carbapenem-nonsusceptible A. baumannii-calcoaceticus complex status
| Carbapenem-nonsusceptible A. baumannii-calcoaceticus complex positive on admission | Carbapenem-nonsusceptible A. baumannii-calcoaceticus complex acquired during ICU stay | Carbapenem-nonsusceptible A. baumannii-calcoaceticus complex negative | p value | |
|---|---|---|---|---|
| n = 69 | (n = 89) | n = 254 | ||
| Age (years), median (IQR) | 47 (33–60) | 48 (35.3–57) | 46 (32–58) | 0.700 |
| Gender (%) | 0.535 | |||
| Male | 35 (50.7) | 42 (47.2) | 137 (53.9) | |
| Female | 34 (49.3) | 47 (52.8) | 117 (46.1) | |
| Underlying diseases (%) | ||||
| Cardiovascular | 0.024 | |||
| Yes | 9 (13.0) | 3 (3.4) | 13 (5.1) | |
| No | 60 (87.0) | 86 (96.6) | 241 (94.9) | |
| Cerebrovascular | 0.001 | |||
| Yes | 3 (4.3) | 14 (15.7) | 12 (4.7) | |
| No | 66 (95.7) | 75 (84.3) | 242 (95.3) | |
| Chronic kidney disease | 0.915 | |||
| Yes | 5 (7.2) | 8 (9.0) | 20 (7.9) | |
| No | 64 (92.8) | 81 (91.0) | 234 (92.1) | |
| Diabetes mellitus | 0.334 | |||
| Yes | 20 (29.0) | 20 (22.5) | 78 (30.7) | |
| No | 49 (71.0) | 69 (77.5) | 176 (69.3) | |
| Malignancy | 0.740 | |||
| Yes | 29 (42.0) | 37 (41.6) | 116 (45.7) | |
| No | 40 (58.0) | 52 (58.4) | 138 (54.3) | |
| Indication for ICU admission (%) | 0.002 | |||
| Medical | 32 (46.4) | 38 (42.7) | 70 (27.6) | |
| Surgical | 37 (53.6) | 51 (57.3) | 184 (72.4) | |
| Referral from (%) | 0.900 | |||
| Other ward this hospital | 38 (55.1) | 48 (53.9) | 136 (53.5) | |
| Other hospital | 14 (20.3) | 14 (15.7) | 49 (19.3) | |
| Directly from Emergency Unit | 17 (24.6) | 27 (30.3) | 69 (27.2) | |
| Antibiotic exposure (pre-ICU admission) | ||||
| Any antibiotic (%) | 58 (84.1) | 73 (82.0) | 180 (70.9) | 0.021 |
| Carbapenem (%) | 24 (34.8) | 22 (24.7) | 33 (13.0) | <0.01 |
| SIRS Score, (%) | 0.916 | |||
| Score ≥ 2 | 64 (92.8) | 81 (91.0) | 232 (91.3) | |
| Score < 2 | 5 (7.2) | 8 (9.0) | 22 (8.7) | |
| qSOFA Score, (%) | 0.089 | |||
| Score ≥ 2 | 51 (73.9) | 78 (87.6) | 205 (80.7) | |
| Score < 2 | 18 (26.1) | 11 (12.4) | 49 (19.3) | |
| Procedures (during ICU admission) | ||||
| Mechanical ventilation (%) | 63 (91.3) | 88 (98.9) | 220 (86.6) | 0.004 |
| Mechanical ventilation (days) median(IQR) | 5 (2–8) | 8 (4–16) | 3 (1–6) | |
| ≥ 5 days (%) | 36 (52.2) | 63 (70.8) | 83 (2.7) | <0.01 |
| < 5 days (%) | 33 (47.8) | 26 (29.2) | 171 (67.3) | |
| Central venous catheter (%) | 66 (95.7) | 85 (95.5) | 212 (83.5) | <0.01 |
| Central venous catheter (days) median(IQR) | 6 (3–9) | 10 (5–17) | 4 (2–7) | |
| ≥ 5 days (%) | 41 (59.4) | 71 (79.8) | 111 (3.7) | <0.01 |
| < 5 days (%) | 28 (40.6) | 18 (20.2) | 143 (56.3) | |
| Urine catheter | 69 (100) | 89 (100) | 254 (100) | N/A |
| Urine catheter (days) median (IQR) | 6 (3–10) | 10 (6–18) | 5 (3–7) | |
| ≥ 5 days (%) | 26 (37.7) | 13 (14.6) | 122 (48.0) | <0.01 |
| < 5 days (%) | 43 (62.3) | 76 (85.4) | 132 (52.0) | |
| Antibiotic therapy (during ICU admission) | ||||
| Any antibiotic (%) | 68 (98.6) | 89 (100) | 249 (98.0) | 0.411 |
| Carbapenem (%) | 42 (60.9) | 62 (69.7) | 95 (37.4) | <0.01 |
| Outcomes | ||||
| Length of stay (days), median (IQR) | 5 (3–9) | 11 (5–18) | 4 (3–7) | <0.01 |
| Death | 22 (31.9) | 38 (42.7) | 59 (23.2) | 0.002 |
