|
Age (years), median (IQR)
|
47 (33–60)
|
48 (35.3–57)
|
46 (32–58)
|
0.700
|
|
Gender (%)
| | | |
0.535
|
|
Male
|
35 (50.7)
|
42 (47.2)
|
137 (53.9)
| |
|
Female
|
34 (49.3)
|
47 (52.8)
|
117 (46.1)
| |
|
Underlying diseases (%)
|
|
Cardiovascular
| | | |
0.024
|
|
Yes
|
9 (13.0)
|
3 (3.4)
|
13 (5.1)
| |
|
No
|
60 (87.0)
|
86 (96.6)
|
241 (94.9)
| |
|
Cerebrovascular
| | | |
0.001
|
|
Yes
|
3 (4.3)
|
14 (15.7)
|
12 (4.7)
| |
|
No
|
66 (95.7)
|
75 (84.3)
|
242 (95.3)
| |
|
Chronic kidney disease
| | | |
0.915
|
|
Yes
|
5 (7.2)
|
8 (9.0)
|
20 (7.9)
| |
|
No
|
64 (92.8)
|
81 (91.0)
|
234 (92.1)
| |
|
Diabetes mellitus
| | | |
0.334
|
|
Yes
|
20 (29.0)
|
20 (22.5)
|
78 (30.7)
| |
|
No
|
49 (71.0)
|
69 (77.5)
|
176 (69.3)
| |
|
Malignancy
| | | |
0.740
|
|
Yes
|
29 (42.0)
|
37 (41.6)
|
116 (45.7)
| |
|
No
|
40 (58.0)
|
52 (58.4)
|
138 (54.3)
| |
|
Indication for ICU admission (%)
| | | |
0.002
|
|
Medical
|
32 (46.4)
|
38 (42.7)
|
70 (27.6)
| |
|
Surgical
|
37 (53.6)
|
51 (57.3)
|
184 (72.4)
| |
|
Referral from (%)
| | | |
0.900
|
|
Other ward this hospital
|
38 (55.1)
|
48 (53.9)
|
136 (53.5)
| |
|
Other hospital
|
14 (20.3)
|
14 (15.7)
|
49 (19.3)
| |
|
Directly from Emergency Unit
|
17 (24.6)
|
27 (30.3)
|
69 (27.2)
| |
|
Antibiotic exposure (pre-ICU admission)
|
|
Any antibiotic (%)
|
58 (84.1)
|
73 (82.0)
|
180 (70.9)
|
0.021
|
|
Carbapenem (%)
|
24 (34.8)
|
22 (24.7)
|
33 (13.0)
|
<0.01
|
|
SIRS Score, (%)
| | | |
0.916
|
|
Score ≥ 2
|
64 (92.8)
|
81 (91.0)
|
232 (91.3)
| |
|
Score < 2
|
5 (7.2)
|
8 (9.0)
|
22 (8.7)
| |
|
qSOFA Score, (%)
| | | |
0.089
|
|
Score ≥ 2
|
51 (73.9)
|
78 (87.6)
|
205 (80.7)
| |
|
Score < 2
|
18 (26.1)
|
11 (12.4)
|
49 (19.3)
| |
|
Procedures (during ICU admission)
|
|
Mechanical ventilation (%)
|
63 (91.3)
|
88 (98.9)
|
220 (86.6)
|
0.004
|
|
Mechanical ventilation (days) median(IQR)
|
5 (2–8)
|
8 (4–16)
|
3 (1–6)
| |
|
≥ 5 days (%)
|
36 (52.2)
|
63 (70.8)
|
83 (2.7)
|
<0.01
|
|
< 5 days (%)
|
33 (47.8)
|
26 (29.2)
|
171 (67.3)
| |
|
Central venous catheter (%)
|
66 (95.7)
|
85 (95.5)
|
212 (83.5)
|
<0.01
|
|
Central venous catheter (days) median(IQR)
|
6 (3–9)
|
10 (5–17)
|
4 (2–7)
| |
|
≥ 5 days (%)
|
41 (59.4)
|
71 (79.8)
|
111 (3.7)
|
<0.01
|
|
< 5 days (%)
|
28 (40.6)
|
18 (20.2)
|
143 (56.3)
| |
|
Urine catheter
|
69 (100)
|
89 (100)
|
254 (100)
|
N/A
|
|
Urine catheter (days) median (IQR)
|
6 (3–10)
|
10 (6–18)
|
5 (3–7)
| |
|
≥ 5 days (%)
|
26 (37.7)
|
13 (14.6)
|
122 (48.0)
|
<0.01
|
|
< 5 days (%)
|
43 (62.3)
|
76 (85.4)
|
132 (52.0)
| |
|
Antibiotic therapy (during ICU admission)
|
|
Any antibiotic (%)
|
68 (98.6)
|
89 (100)
|
249 (98.0)
|
0.411
|
|
Carbapenem (%)
|
42 (60.9)
|
62 (69.7)
|
95 (37.4)
|
<0.01
|
|
Outcomes
|
|
Length of stay (days), median (IQR)
|
5 (3–9)
|
11 (5–18)
|
4 (3–7)
|
<0.01
|
|
Death
|
22 (31.9)
|
38 (42.7)
|
59 (23.2)
|
0.002
|
