Synergistic effect of eugenol with Colistin against clinical isolated Colistin-resistant Escherichia coli strains

Table 4 MIC and FICI of eugenol and colistin against Escherichia coli strains

Strains	Agents	MIC (μg/mL)		FICI	Outcome
Strains	Agents	Alone	Combination	FICI	Outcome
ATCC 25922	Eugenol	4	1	0.5	Synergy
ATCC 25922	Colistin	1	0.25	0.5	Synergy
E. coli Porcine1	Eugenol	4	2	0.625	partial synergy
E. coli Porcine1	Colistin	8	2	0.625	partial synergy
E. coli Porcine2	Eugenol	4	1	0.375	Synergy
E. coli Porcine2	Colistin	8	1	0.375	Synergy
E. coli Porcine3	Eugenol	4	1	0.5	Synergy
E. coli Porcine3	Colistin	8	2	0.5	Synergy
E. coli Duck	Eugenol	4	2	0.625	partial synergy
E. coli Duck	Colistin	2	0.25	0.625	partial synergy
E. coli Goose1	Eugenol	4	1	0.5	Synergy
E. coli Goose1	Colistin	2	0.5	0.5	Synergy
E. coli Goose2	Eugenol	4	1	0.5	Synergy
E. coli Goose2	Colistin	4	1	0.5	Synergy
E. coli Goose3	Eugenol	4	1	0.5	Synergy
E. coli Goose3	Colistin	4	1	0.5	Synergy
E. coli Goose4	Eugenol	4	2	0.625	partial synergy
E. coli Goose4	Colistin	16	2	0.625	partial synergy
E. coli Peacock	Eugenol	8	4	0.625	partial synergy
E. coli Peacock	Colistin	2	0.25	0.625	partial synergy
E. coli Zebra	Eugenol	4	1	0.375	Synergy
E. coli Zebra	Colistin	2	0.25	0.375	Synergy
E. coli Fox	Eugenol	4	1	0.625	partial synergy
E. coli Fox	Colistin	4	1	0.625	partial synergy
E. coli Bovine	Eugenol	4	2	0.625	partial synergy
E. coli Bovine	Colistin	16	2	0.625	partial synergy
E. coli Avian	Eugenol	8	2	0.5	Synergy
E. coli Avian	Colistin	2	0.5	0.5	Synergy

ISSN: 2047-2994