Table 3 Treatment related variables, univariate analyses between cases and controls 1&2 and between cases and controls 3&4

82 (59.4)

79 (28.0)^b

4.863 (2.886–8.194)

< 0.001

50 (17.7)^b

5.890 (3.647–9.512)

< 0.001

16 (11.6)

19 (6.7)^b

1.913 (0.899–4.071)

0.092

17 (6.0)^b

2.053 (1.011–4.169)

0.047

51 (37.0)

53 (18.8)

2.988 (1.769–5.046)

< 0.001

24 (8.5)

6.832 (3.692–12.643)

< 0.001

39 (29.1)

48 (17.0)^b

2.014 (1.196–3.394)

0.009

40 (14.2)^b

2.388 (1.428–3.992)

0.001

58 (42.0)

58 (20.7)

3.124 (1.898–5.142)

< 0.001

26 (9.2)

6.762 (3.810–12.000)

< 0.001

104 (77.6)

131 (46.5)

3.942 (2.383–6.520)

< 0.001

107 (37.9)

6.407 (3.692–11-121)

< 0.001

17 (12.7)

20 (7.1)^b

1.896 (0.926–3.880)

0.080

12 (4.3)^b

4.282 (1.756–10.437)

0.001

60 (44.8)

64 (22.7)

2.702 (1.696–4.304)

< 0.001

27 (9.6)

6.881 (3.885–12.190)

< 0.001

48 (35.8)

48 (17.0)

2.445 (1.534–3.898)

< 0.001

32 (11.3)^b

4.689 (2.630–8.360)

< 0.001

17 (12.7)

12 (4.3)^b

3.486 (1.543–7.878)

0.003

24 (8.5)

1.527 (0.767–3.039)

0.228

29 (21.6)

49 (17.4)

1.226 (0.739–2.032)

0.431

31 (11.0)

2.100 (1.199–3.678)

0.009

49 (36.6)

50 (17.7)^b

2.774 (1.666–4.621)

< 0.001

32 (11.3)^b

4.572 (2.604–8.025)

< 0.001

94 (70.1)

88 (31.2)

6.087 (3.553–10.429)

< 0.001

53 (18.8)

9.193 (5.284–15.996)

< 0.001

32 (23.9)

23 (8.2)^b

3.606 (1.930–6.740)

< 0.001

19 (6.7)^b

3.834 (2.098–7.007)

< 0.001

74 (55.2)

51 (18.1)

6.355 (3.652–11.057)

< 0.001

27 (9.6)

9.847 (5.437–17.836)

< 0.001

32 (23.9)

28 (9.9)^b

3.074 (1.680–5.627)

< 0.001

30 (10.6)^b

2.684 (1.512–4.763)

0.001

92 (68.7)

109 (38.7)

4.583 (2.641–7.952)

< 0.001

59 (20.9)

10.864 (5.748–20.536)

< 0.001