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Table 2 Antibiotic susceptibility of NMD5-producing isolates and their transconjugants

From: Dissemination of blaNDM-5 gene via an IncX3-type plasmid among non-clonal Escherichia coli in China

Isolates MICs (mg/L)
FEP IPM NIT CAZ AMK CIP ATM TGC CPS2/1 MNO COL
EC126 > 128 8 128 > 128 > 128 128 > 128 0.5 > 256 8 0.5
EC135 64 16 64 > 128 128 128 0.125 2 > 256 32 0.5
KP387 64 16 128 > 128 1 2 0.25 4 > 256 32 0.5
JH387 64 16 16 > 128 0.5 0.5 0.25 0.5 > 256 4 0.5
EC463 > 128 64 8 > 128 1 64 32 2 > 256 64 0.5
JH 463 128 64 16 > 128 1 0.125 0.125 0.25 > 256 2 < 0.25
EC734 64 8 8 > 128 1 64 4 0.25 > 256 32 0.5
JH734 64 16 16 > 128 0.5 0.25 0.125 0.5 > 256 2 < 0.25
EC611 32 8 8 > 128 1 0.0625 0.0625 0.25 > 256 2 0.25
JH611 64 8 8 > 128 0.5 0.0625 0.125 0.5 > 256 2 0.25
EC144 128 32 32 > 128 > 128 64 128 0.25 > 256 32 0.5
JH144 128 16 32 > 128 0.5 0.5 0.125 0.5 > 256 2 < 0.25
EC122 > 128 32 64 > 128 > 128 64 > 256 8 > 256 128 0.5
JH122 128 16 16 > 128 0.5 0.5 0.125 0.5 > 256 2 < 0.25
EC418 32 8 32 > 128 1 0.25 0.125 1 > 256 48 0.5
JH418 32 8 16 > 128 0.5 0.25 0.125 0.5 > 256 2 < 0.25
CF418 32 32 8 > 128 1 0.25 0.l25 0.5 > 256 4 0.5
JHF418 16 8 8 > 128 1 0.25 0.125 0.5 > 256 2 < 0.25
EC310 > 128 128 8 > 128 1 8 0.19 0.5 > 256 2 0.5
JHE310 > 128 64 8 > 128 0.5 0.5 0.125 0.5 > 256 1 < 0.25
EC600 0.125 0.5 8 0.25 0.5 0.125 0.25 0.125 0.5 1 < 0.25
ATCC25922a 0.125 0.5 < 8 0.125 0.5 0.125 0.125 0.125 0.25 0.25 < 0.25
  1. FEP cefepime, IMP imipenem, NIT nitrofurantoin, CAZ ceftazidime, AMK amikacin, CIP ciprofloxacin, ATM aztreonam, TGC tigecycline, MNO minocycline, CPS cefperazone/sulbactam, COL colistin
  2. All susceptibility tests were repeated at least three times according to CLSI method. The results of colistin susceptibility were interpreted according to EUCAST breakpoints
  3. aquality control strain
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