Table 1 Baseline characteristics of the study population by years

Parameters

Total

2011

2012

2013

2014

2015

2016

p-value

No of pts. (%)

No of pts. (%)

No of pts. (%)

No of pts. (%)

No of pts. (%)

No of pts. (%)

Patients, total

2038

313 (100%)

350 (100%)

361 (100%)

341 (100%)

326 (100%)

347 (100%)

1.000

Children

345 (16.9%)

52 (16.6%)

57 (16.3%)

58 (16.1%)

65 (19.1%)

42 (12.9%)

71 (20.5%)

0.315

Male gender

1020 (50%)

154 (49.2%)

184 (52.6%)

186 (51.5%)

168 (49.3%)

164 (50.3%)

164 (47.3%)

0.976

Diagnosis

Brain trauma

255 (12.5%)

43 (13.7%)

54 (15.4%)

51 (14.1%)

41 (12.0%)

28 (8.6%)

38 (11.0%)

0.192

Brain tumor

1271 (62.4%)

185 (59.1%)

221 (63.1%)

240 (66.5%)

200 (58.7%)

209 (64.1%)

216 (62.2%)

0.911

Congenital disorders

23 (1.1%)

4 (1.3%)

5 (1.4%)

3 (0.8%)

7 (2.1%)

2 (0.6%)

2 (0.6%)

0.436

Vascular brain diseases

454 (22.3%)

77 (24.6%)

60 (17.1%)

63 (17.5%)

89 (26.1%)

80 (24.5%)

85 (24.5%)

0.066

Other diseases

29 (1.4%)

3 (1.0%)

10 (2.9%)

4 (1.1%)

4 (1.2%)

4 (1.2%)

4 (1.2%)

0.302

Surgeries

Craniotomy

1537 (75.4%)

230 (73.5%)

261 (74.6%)

279 (77.3%)

262 (76.8%)

245 (75.2%)

260 (74.9%)

0.998

INSD

650 (31.9%)

101 (32.3%)

130 (37.1%)

124 (34.3%)

112 (32.8%)

94 (28.8%)

89 (25.6%)

0.227

Endovascular surgery

194 (9.5%)

31 (9.9%)

37 (10.6%)

26 (7.2%)

40 (11.7%)

25 (7.7%)

35 (10.1%)

0.407

EETS

87 (4.3%)

13 (4.2%)

15 (4.3%)

15 (4.2%)

14 (4.1%)

15 (4.6%)

15 (4.3%)

1.000

Spinal surgery

4 (0.2%)

1 (0.3%)

0 (0.0%)

0 (0.0%)

0 (0.0%)

2 (0.6%)

1 (0.3%)

0.377

Other surgeries

873 (42.8%)

151 (48.2%)

161 (46.0%)

156 (43.2%)

146 (42.8%)

127 (39.0%)

132 (38.0%)

0.523

Outcomes

Recovery

80 (3.9%)

15 (4.8%)

14 (4.0%)

14 (3.9%)

19 (5.6%)

9 (2.8%)

9 (2.6%)

0.365

Positive dynamics

934 (45.8%)

133 (42.5%)

153 (43.7%)

170 (47.1%)

159 (46.6%)

150 (46.0%)

169 (48.7%)

0.934

No dynamics

210 (10.3%)

34 (10.9%)

41 (11.7%)

37 (10.2%)

30 (8.8%)

29 (8.9%)

39 (11.2%)

0.818

Negative dynamics

505 (24.8%)

81 (25.9%)

67 (19.1%)

78 (21.6%)

92 (27.0%)

96 (29.4%)

91 (26.2%)

0.153

Death

307 (15%)

50 (16.0%)

75 (21.4%)

62 (17.2%)

41 (12.0%)

41 (12.6%)

38 (11.0%)

0.009

Median [Q1;Q3]

Median [Q1;Q3]

Median [Q1;Q3]

Median [Q1;Q3]

Median [Q1;Q3]

Median [Q1;Q3]

Median [Q1;Q3]

p-value

Age, years

46 [26.0; 59.0]

44 [25.0; 57.0]

44 [25.0; 58.0]

47 [26.0; 60.0]

44 [25.0; 57.0]

50 [30.0; 59.75]

48 [24.5; 60.5]

0.099

CCI score

3 [2.0; 5.0]

3 [2.0; 4.0]

3 [2.0; 5.0]

3 [2.0; 5.0]

3 [2.0; 4.0]

3 [2.0; 5.0]

3 [2.0; 4.0]

1.000

Length of stay in ICU, days

10 [6.0; 22.0]

13 [7.0; 27.0]

12 [6.0; 25.0]

10 [6.0; 24.0]

8 [6.0; 22.0]

9 [6.0; 22.0]

8 [5.0; 17.0]

0.010