Table 3 Univariate analysis of factors which may have contributed to decolonization. Variables are compared between colonized and decolonized patients, using Fisher’s exact test
Variables | Colonized (n = 60) | Decolonized (n = 56) | p-value (α = 0.05) |
|---|---|---|---|
Age, mean ± SD | 61 ± 20.9 | 66 ± 18.4 | 0.17 |
Patients with a Charlson Comorbidity Index (CCI) < 5a, n (%) | 35 (58.4) | 28 (50.0) | 0.46 |
Elapsed time in days to detect XDR consideration admission, median (min-max) | 2 (− 420–101) | 0 (−609–127) | 0.34 |
Duration of hospitalization in days, median (min-max) | 9 (1–273) | 16.5 (2–290) | 0.02 |
Duration of follow-up in days considering discharge, median (min-max) | 7 (0–721) | 99 (0–974) | < 0.0001 |
Antibiotic exposure prior to colonization, n (%) | 21 (35.0) | 25 (44.6) | 0.34 |
Antibiotic exposure after being colonized, n (%) | 12 (21.4) | 5 (8.3) | 0.06 |
Pooled duration of antibiotic regimen in days, mean ± SD | 19.6 ± 15.3 | 21.1 ± 17.6 | 0.83 |
Occurrence of a sepsis due to XDR bacteria, n (%) | 3 (5.0) | 3 (5.4) | 0.99 |
Carrying a CRE, n (%) | 44 (73.3) | 38 (67.9) | 0.55 |
Harboring an OXA-48 CRE, n (%) | 33 (55.0) | 25 (44.7) | 0.35 |
Returning back home, n (%) | 43 (71.7) | 44 (78.6) | 0.52 |
Being transfer to another facility including rehabilitation, n (%) | 7 (11.7) | 9 (16.1) | 0.59 |
Unfavorable outcome (death), n (%) | 8 (13.3) | 2 (3.6) | 0.1 |