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Table 3 Univariate analysis of factors which may have contributed to decolonization. Variables are compared between colonized and decolonized patients, using Fisher’s exact test

From: Germs of thrones - spontaneous decolonization of Carbapenem-Resistant Enterobacteriaceae (CRE) and Vancomycin-Resistant Enterococci (VRE) in Western Europe: is this myth or reality?

Variables Colonized (n = 60) Decolonized (n = 56) p-value (α = 0.05)
Age, mean ± SD 61 ± 20.9 66 ± 18.4 0.17
Patients with a Charlson Comorbidity Index (CCI) < 5a, n (%) 35 (58.4) 28 (50.0) 0.46
Elapsed time in days to detect XDR
consideration admission, median (min-max)
2 (− 420–101) 0 (−609–127) 0.34
Duration of hospitalization in days, median (min-max) 9 (1–273) 16.5 (2–290) 0.02
Duration of follow-up in days considering discharge, median (min-max) 7 (0–721) 99 (0–974) < 0.0001
Antibiotic exposure prior to colonization, n (%) 21 (35.0) 25 (44.6) 0.34
Antibiotic exposure after being colonized, n (%) 12 (21.4) 5 (8.3) 0.06
Pooled duration of antibiotic regimen in days, mean ± SD 19.6 ± 15.3 21.1 ± 17.6 0.83
Occurrence of a sepsis due to XDR bacteria, n (%) 3 (5.0) 3 (5.4) 0.99
Carrying a CRE, n (%) 44 (73.3) 38 (67.9) 0.55
Harboring an OXA-48 CRE, n (%) 33 (55.0) 25 (44.7) 0.35
Returning back home, n (%) 43 (71.7) 44 (78.6) 0.52
Being transfer to another facility including rehabilitation, n (%) 7 (11.7) 9 (16.1) 0.59
Unfavorable outcome (death), n (%) 8 (13.3) 2 (3.6) 0.1
  1. aCohort was divided according to CCI median equal to 5. Patients with a CCI scores ≥5 are considered as severe and fragile
  2. Bold data are significant and italicized is a trend to significant result