From: Optimal timing of surgical antimicrobial prophylaxis in laparoscopic surgery: a before-after study
Pre-intervention (n = 942) | Intervention (n = 455) | P value | |
---|---|---|---|
Age, median, (IQR) years | 66 (52–75) | 68 (55–76) | 0.04 |
Male gender, n (%) | 431 (56.4) | 260 (57.1) | 0.79 |
Co-morbidities, n (%) | |||
Diabetes mellitus | 129 (13.7) | 63 (13.8) | 0.94 |
Chronic lung diseases | 42 (4.5) | 27 (5.9) | 0.23 |
Cardiovascular diseases | 37 (3.9) | 32 (7.0) | 0.01 |
Hypertension | 333 (35.4) | 180 (39.6) | 0.14 |
Dyslipidemia | 158 (16.8) | 73 (16.0) | 0.76 |
Current smoker, n (%) | 446 (47.4) | 224 (49.2) | 0.51 |
ASA score, n (%) | |||
1 no disturbance | 207 (22.0) | 72 (15.8) | Ref. |
2 mild disturbance | 654 (69.4) | 344 (75.6) | 0.01 |
3 severe disturbance | 79 (8.4) | 37 (8.1) | 0.22 |
4 life-threatening | 2 (0.2) | 2 (0.4) | 0.30 |
Wound class, n (%) | |||
2 clean-contaminated | 936 (99.4) | 454 (99.8) | 0.44 |
3 contaminated | 6 (0.6) | 1 (0.2) | 0.44 |
Emergent operation, n (%) | 152 (16.1) | 70 (15.4) | 0.72 |
Type of surgery, n (%) | |||
Gastrectomy | 242 (25.7) | 129 (28.4) | 0.29 |
Cholecystectomy | 213 (22.6) | 94 (20.7) | 0.41 |
Appendectomy | 125 (13.3) | 32 (7.0) | 0.001 |
Colectomy | 130 (13.8) | 70 (15.4) | 0.43 |
Proctectomy | 231 (24.5) | 130 (28.6) | 0.11 |
Cholecystectomy and appendectomy | 1 (0.1) | 0 (0) | N/A |
Operation time, median, (IQR) min | 213 (133–286) | 222 (145–322) | 0.003 |