The impact of the national action plan on the epidemiology of antibiotic resistance among 352,238 isolates in a teaching hospital in China from 2015 to 2018

Table 2 Multivariate logistical regression on antimicrobial resistance before and after action plan (n = 352,238)

Items	aOR	95% CI	p
Sex
Female	0.87	0.85–0.89	< 0.001
Male	1
Age
0–49	1
50–80	1.12	1.09–1.16	< 0.001
81–102	1.15	1.11–1.19	< 0.001
Department
ICU	1
Ward	0.38	0.37–0.39	< 0.001
Outpatient clinics	0.32	0.31–0.34	< 0.001
Sample type
Blood	1
Urine	1.51	1.44–1.57	< 0.001
Sputum	1.74	1.66–1.81	< 0.001
Other	0.8	0.77–0.84	< 0.001
Diseases
Hypertension	1
Hypoproteinemia	2.36	2.12–2.63	< 0.001
Pneumonia	1.39	1.34–1.45	< 0.001
Chronical-bronchitis	1.44	1.33–1.56	< 0.001
Anemia	1.25	1.15–1.36	< 0.001
Brain diseases	1.22	1.17–1.27	< 0.001
Fracture	1.18	1.09–1.27	< 0.001
Prostatic hyperplasia	1.18	1.12–1.25	< 0.001
Appendicitis	1.09	1.03–1.45	0.002
Heart diseases	1.04	0.88–1.46	0.135
Kidney diseases	0.98	0.92–1.04	0.509
Diabetes	0.94	0.90–0.99	0.013
Perianal abscess	0.92	0.84–1.0	0.043
Urinary tract infection	0.76	0.72–0.81	0.002
Group
Before NAP	1
After NAP	0.79	0.77–0.80	< 0.001

Notes: Other = catheter, drainage, secretion and body fluid. NAP = national action plan

ISSN: 2047-2994