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Table 3 Microbiology test ordering practices

From: Use of microbiology tests in the era of increasing AMR rates– a multicentre hospital cohort study

 

Microbiology test

Blood culture

Urine culture

SST culture1

Resp. test2

Diagnosis*

Hospital

 

%

p3

%

p3

%

p3

%

p3

Sepsis

Hospital A

n = 205

95.1

0.64

70.2

0.02

10.7

< 0.01

60.0

< 0.01

Hospital B

n = 42

88.1

0.06

76.2

0.81

2.4

0.34

78.6

< 0.01

Hospital C

n = 73

97.3

0.38

86.3

0.01

1.4

0.02

17.8

< 0.01

Total

n = 320

94.7

74.7

 

52.8

 

7.5

 

UTI

Hospital A

n = 67

59.7

0.77

91.0

0.64

3.0

0.27

31.3

0.02

Hospital B

n = 50

70.0

0.05

90.0

0.54

2.0

1.00

36.0

< 0.01

Hospital C

n = 77

49.4

0.04

94.8

0.28

0.0

0.28

3.9

< 0.01

Total

n = 194

58.2

 

92.3

1.5

21.6

 

SSTI

Hospital A

n = 97

80.4

0.97

14.4

< 0,01

68.0

< 0.01

8.2

0.66

Hospital B

n = 54

79.6

0.89

13.0

0.04

44.4

0.16

11.1

0.22

Hospital C

n = 52

80.8

0.92

50.0

< 0,01

32.7

< 0.01

1.9

0.12

Total

n = 203

80.3

 

23.2

 

52.7

 

7.4

 

LRTI

Hospital A

n = 287

80.8

0.07

48.4

0.73

1.0

0.51

68.3

< 0.01

Hospital B

n = 164

75.0

0.36

40.2

0.01

1.8

0.71

89.0

< 0.01

Hospital C

n = 155

74.2

0.25

60.0

< 0,01

1.9

0.70

20.0

< 0.01

Total

n = 606

77.6

49.2

1.5

61.6

AECOPD

Hospital A

n = 172

74.4

< 0.01

38.4

0.42

2.3

0.46

59.3

0.29

Hospital B

n = 152

57.9

0.01

33.6

0.02

1.3

1.00

92.1

< 0.01

Hospital C

n = 84

63.1

0.54

58.3

< 0.01

1.2

1.00

14.3

< 0.01

Total

n = 408

65.9

40.7

1.7

62.3

All

Total

n = 1731

76.1

53.7

8.7

49.3

  1. *AECOPD: acute exacerbation of chronic obstructive pulmonary disease; LRTI: lower respiratory infection; SSTI: skin and soft tissue infection; UTI: urinary tract infection
  2. 1SST culture: wound, pus, breastmilk or tissue culture
  3. 2Resp. test: respiratory culture, polymerase chain reaction (PCR) test for viral and bacterial respiratory pathogens and/or urinary pneumococcal antigen test
  4. 3p value for testing whether there is a significant difference between one hospital compared to the total frequencies of the two others by Chi-square test or by Fisher’s exact test when numbers in one or more categories were < 5