Skip to main content

Table 2 Accordance of the package sizes of selected drugs with guidelines for sore throat II

From: Evaluation of accordance of antibiotics package size with recommended treatment duration of guidelines for sore throat and urinary tract infections

Drug Package size ISKRAa Min No. of Packages Extra units IDSAb Min No. of Packages Extra units NICEc Min No. of Packages Extra units
Clarithromycin 14x250 mgd 2x250 mg, 10 days 2 8 2x250 mg, 10 days 2 8 2x250-500 mg, 5 days 1 4
5x500 mg 2x250 mg, 10 days n/a 2x250 mg, 10 days n/a 2x250-500 mg, 5 days 2 0
7x500 mgd 2x250 mg, 10 days n/a 2x250 mg, 10 days n/a 2x250-500 mg, 5 days 2 4
14x500 mgd 2x250 mg, 10 days n/a 2x250 mg, 10 days n/a 2x250-500 mg, 5 days 1 4
Penicillin V 30x1000000 IUd 3x1 500 000 IU, 10 days 2 15 4x250 mg, 10 days n/a 4x500 mg, 5-10 days n/a
2x500 mg, 10 days 2x1000 mg, 5-10 days
30x1500000 IUd 3x1 500 000 IU, 10 days 1 0 4x250 mg, 10 days n/a 4x500 mg, 5-10 days n/a
2x500 mg, 10 days 2x1000 mg, 5-10 days
Erythromycin 16x250 mgd n/a n/a 4x250-500 mg, 5 days 3 8
2x500-1000 mg, 5 days 3 8
  1. n/a – not applicable; IU-international unit; extra units of drugs are presented with reference to the original formulation
  2. aThe Intersectoral Society for Antibiotic Resistance Control (ISKRA) guidelines on sore throat: diagnostic and therapeutic approach – Croatian national guidelines
  3. bClinical Practice Guideline for the Diagnosis and Management of Group A Streptococcal Pharyngitis: 2012 Update by the Infectious Diseases Society of America
  4. cNational Institute for Health and Care Excellence (NICE) Sore throat (acute): antimicrobial prescribing
  5. dincluded in Croatian national reimbursement lists on 1st of August 2018