Table 2 Technological characteristics of the DOX-SLN formulation: average diameter, polydispersity index and zeta potential during stability study, (Means ± SD, n = 3)
Technological parameters | Time (months) | |||||
|---|---|---|---|---|---|---|
0 | 1 | 2 | 4 | 8 | 12 | |
Average diameter nm (±SD) | 299±34 | 301±34 | 300±34 | 305±34 | 311±34 | 320±34 |
Polydispersity index | 0.290 ±0.027 | 0.292±0.012 | 0.295±0.031 | 0.299±0.024 | 0.316±0.017 | 0.401±0.045 |
Zeta potential (mV ± SD) | −28.7±3.2 | −29.2±2.9 | −24.1±3.6 | −31.9±4.0 | −21.9±1.8 | −26.2±2.7 |