Skip to main content

Table 3 Genotype characteristics and MIC ranges of four antimicrobial agents against 154 M. pneumoniae clinical isolates from five areas, 2017 to 2018

From: Antimicrobial susceptibility and molecular characteristics of Mycoplasma pneumoniae isolates across different regions of China

Region Mutation in the 23S rRNA Isolates number MIC (μg/ml)
Genotype I Genotype II ERY AZM LVX TET
Beijing A2063G 30 4 128- > 256 2–32 0.125–1 0.016–0.125
None 1 16 < 0.008 < 0.008 0.125–0.5 0.032–0.125
Jilin, Jilin A2063G 48 0 128- > 256 2–32 0.125–0.5 0.016–0.25
A2064G 1 0 > 256 2 0.5 0.125
Soochow, Jiangsu A2063G 22 0 ≥256 2–16 0.125–1 0.016–0.125
None 0 2 < 0.008 < 0.008 0.25–0.5 0.032
Jinan, Shangdong A2063G 8 3 128- > 256 2–32 0.125–1 0.032–0.125
A2064G 1 0 256 2 0.5 0.032
None 1 9 < 0.008 < 0.008 0.125–0.5 0.016–0.125
Fuyang, Anhui A2063G 6 0 > 256 4–16 0.125–0.5 0.032–0.125
None 0 2 < 0.008 < 0.008 0.25–0.5 0.032–0.125
Total A2063G 114 7 128- > 256 2–32 0.125–1 0.016–0.25
A2064G 2 0 ≥256 2 0.5 0.032–0.125
None 2 29 < 0.008 < 0.008 0.125–0.5 0.016–0.125
  1. The MIC of each agent was defined as the lowest concentration of each antibiotic that prevented the color change
  2. ERY erythromycin, AZM azithromycin, LVX levofloxacin, TET tetracycline