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Table 2 Indications for linezolid use. Data from the national point prevalence surveys 2011 and 2016. Data comparison of the two surveys

From: Linezolid use in German acute care hospitals: results from two consecutive national point prevalence surveys

Indication

Variable

Site of infection

Number (percentage)

p-value

PPS 2011

PPS 2016

All

Total

 

119 (100)

255 (100)

n.a.

Treatment (CI + LI + HI)

Total

 

104 (87.4)

232 (91.0)

0.29

Site of infection (CI+ LI+ HI)

All

104 (100)

232 (100)

 

Bacteremia

10 (9.6)

27 (11.6)

0.38 (a)

Non-laboratory confirmed systemic infection

9 (8.7)

18 (7.8)

Bone/Joint infection

10 (9.6)

28 (12.1)

Skin/Soft tissue infection

21 (20.2)

55 (23.7)

Intraabdominal infection

5 (4.8)

23 (9.9)

Lower respiratory tract infection

27 (26.0)

42 (18.1)

Urinary tract infection

4 (3.8)

12 (5.2)

Other/Not specified

18 (17.3)

27 (11.6)

Treatment CI + LI

Total

 

43 (36.1)

103 (40.4)

0.44

Site of infection (CI + LI)

All

43 (100)

103 (100)

 

Bacteremia

3 (7.0)

9 (8.7)

0.21 (a)

Non-laboratory confirmed systemic infection

4 (9.3)

5 (4.9)

Bone/Joint infection

4 (9.3)

11 (10.7)

Skin/Soft tissue infection

8 (18.6)

28 (27.2)

Intraabdominal infection

0 (0)

11 (10.7)

Lower respiratory infection

13 (30.2)

19 (18.4)

Urinary tract infection

2 (4.7)

6 (5.8)

Other/Not specified

9 (20.9)

14 (13.6)

Treatment HI

Total

 

61 (51.3)

129 (50.6)

0.90

Site of infection (HI)

All

61 (100)

129 (100)

 

Bacteremia

7 (11.5)

18 (14.0)

0.94 (a)

Non-laboratory confirmed systemic infection

5 (8.2)

13 (10.1)

Bone/Joint infection

6 (9.8)

17 (13.2)

Skin/Soft tissue infection

13 (21.3)

27 (20.9)

Intraabdominal infection

5 (8.2)

12 (9.3)

Lower respiratory infection

14 (23.0)

23 (17.8)

Urinary tract infection

2 (3.3)

6 (4.7)

Other/Not specified

9 (14.8)

13 (10.1)

Other/Unknown

  

15 (12.6)

23 (9.0)

0.29

  1. Except where specified otherwise, p-values were calculated using Chi-squared test. Abbreviations: PPS point prevalence survey, CI community-acquired infection, LI infection acquired in long-term care, HI hospital-acquired infection, n.a. not applicable; (a) p-values were calculated for all listed sites of infection collectively using R by C tables