Fig. 3

Lateral radiographs of tibiae in different groups, taken before and 1 day, 3 and 6 weeks after debridement. a 3 weeks after infection induction, the tibia showed a typical character of chronic osteomyelitis, including periosteal new bone formation (white arrow), bone destruction (black arrow), and sequestra (black arrows). The tibiae in the NBD + Van group have shown a gradually healing of osteomyelitis after treatment (b, c, and d), whereas the tibial osteomyelitis in other groups did not ameliorate obviously (e, f, and g)