Table 5 Characteristics of the articles that were included in the meta-analysis and reported resistance to linezolid
First name | Time of study | Published time | Country | Total staphylococcus | S. aureus | MRSA | CoNS | S. aureus Linezolid-Resistant | MRSA Linezolid - Resistant | CoNS Linezolid-Resistant | Susceptibility testing method | Isolation source |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mendes [75] | 2007–2009 | 2010 | USA | 4077 | 4077 | 4077 | 5 | 5 | BMD | Bacteraemia, Pneumonia | ||
Cassettari [28] | 2010–2011 | 2011 | Spain | 299 | 237 | 113 | 62 | 1 | 1 | 1 | BMD | Skin and soft tissue infections, hospital-acquired pneumonia |
Jain [55] | 2011–2014 | 2015 | India | 2008 | 2008 | 384 | 3 | 3 | E-test | |||
Duncan [37] | 2013–2014 | 2016 | USA | 1353 | 1353 | 676 | 1 | 1 | BMD | Pneumonia | ||
Farrell [39] | 2008–209 | 2011 | USA | 4073 | 3257 | 1673 | 816 | 5 | 5 | 12 | BMD | Bacteraemia, Pneumonias, Wound infection, Pneumonia |
Błażewicz [24] | 2014–2015 | 2016 | Poland | 157 | 157 | 11 | 3 | BMD | Skin, Nasal swab | |||
Picazo [85] | 2010 | 2011 | Spain | 702 | 503 | 187 | 199 | 2 | 2 | 16 | BMD | Medical centers |
Sader [92] | 2005–2009 | 2010 | brazil | 2637 | 2637 | 846 | 2 | BMD | Medical centers | |||
Jevitt [57] | 1996–2001 | 2003 | USA | 119 | 88 | 47 | 31 | 1 | BMD | Medical centers | ||
Cuny [32] | 2011–2013 | 2015 | Germany | 1952 | 1952 | 1952 | 1 | 1 | BMD | Blood | ||
Sader [103] | 2002–2004 | 2006 | Greece | 185 | 128 | 57 | 1 | BMD | Skin infection, Blood | |||
Campanile [27] | 2012 | 2015 | Italy | 1684 | 1684 | 640 | 5 | 3 | Automated VITEK-2 system, Broth microdilution | Lower respiratory tract, Skin and Soft tissue | ||
Picazo [82] | 2008 | 2009 | Spain | 703 | 520 | 201 | 183 | 6 | 6 | 3 | BMD | Blood |
Sader [100] | 2007–2008 | 2009 | USA | 9230 | 8077 | 4514 | 1153 | 4 | 4 | 20 | BMD | Blood, Skin, Pneumonia |
Fuchs [44] | 2000–2002 | 2002 | USA | 108 | 53 | 28 | 55 | 1 | 1 | BMD | Medical centers | |
Sader [97] | 2002–2006 | 2008 | USA | 6497 | 6497 | 3143 | 1530 | 6 | 6 | BMD | Blood | |
Farrell [38] | 2008 | 2009 | USA | 4012 | 3156 | 1752 | 856 | 3 | 3 | 18 | Broth microdilution, E-test | Pneumonia, Wound, Urinary tract |
Jones [61] | 2007 | 2009 | Ireland | 141 | 130 | 11 | 1 | BMD | Blood | |||
Jones [63] | 2007 | 2008 | USA | 4338 | 3318 | 1930 | 1920 | 2 | 2 | 18 | BMD | Medical centers |
Jones [60] | 2006 | 2007 | USA | 3721 | 2913 | 1648 | 808 | 1 | 1 | 13 | BMD | Pneumonia, Wound, Urinary tract |
Ross [90] | 2002 | 2005 | USA | 4557 | 3687 | 1401 | 870 | 1 | 1 | 1 | BMD | Medical centers |
Mendes [73] | 2002–2004 | 2008 | USA | 1989 | 1989 | 1989 | 1 | 1 | BMD | Medical centers | ||
Flamm [40] | 2010 | 2012 | USA | 4049 | 3105 | 1578 | 944 | 2 | 2 | 14 | BMD | Blood, Pneumonia, Skin |
Flamm [40] | 2013 | 2015 | USA | 3433 | 3035 | 1454 | 398 | 2 | 2 | 3 | BMD | Blood, skin, soft tissue |
Putnam [86] | 2004–2008 | 2010 | USA | 18,917 | 18,917 | 10,242 | 3 | 3 | BMD | Bacteraemia, Pneumonia | ||
Pfaller [81] | 2011–2015 | 2017 | USA | 6741 | 3031 | 1391 | 924 | 1 | 1 | 7 | BMD | Medical centers |
Flamm [42] | 2014 | 2016 | USA | 3903 | 3106 | 797 | 2 | 2 | 5 | BMD | Blood, Pneumonia, Skin | |
Sahm [105] | 2011–2012 | 2015 | USA | 4186 | 3743 | 443 | 5 | 2 | BMD | Medical centers | ||
Tekin [108] | 2007–2011 | 2014 | Turkey | 870 | 90 | 771 | 1 | 1 | 14 | E-test | Blood | |
Rosenthal [89] | 2012 | 2014 | Haiti | 16 | 16 | 4 | 1 | E-test | Different ward of hospital | |||
Decousser [33] | 2004–2016 | 2018 | France | 3437 | 3437 | 953 | 3 | BMD | All body sites | |||
Sader [96] | 2008–2014 | 2016 | USA | 670 | 670 | 339 | 2 | 1 | BMD | Skin infection | ||
Hodille [51] | 2010–2014 | 2016 | France | 440 | 440 | 325 | 2 | 2 | BMD | Bronchopulmonary infections | ||
Sader [94] | 2009–2013 | 2015 | USA | 4426 | 4426 | 2013 | 1 | 1 | BMD | Blood | ||
Sader [95] | 2008–2011 | 2013 | USA | 22,620 | 19,350 | 9872 | 3270 | 14 | 9 | 51 | BMD | Blood, Respiratory tract, Skin |
Mendes [74] | 2007–2009 | 2012 | USA | 9282 | 8042 | 4278 | 1240 | 4 | 4 | 19 | BMD | Bacteraemia, Respiratory tract |
Richter [87] | 2009 | 2011 | USA | 4210 | 4210 | 2247 | 1 | 1 | BMD | Wound, Blood, Lower respiratory tract, Joint fluid | ||
Gales [45] | 2005–2008 | 2009 | Brazil | 3030 | 2218 | 687 | 812 | 1 | 1 | 2 | BMD | Blood, Skin, Pneumonia |
Sader [98] | 2002–2006 | 2009 | USA | 14,009 | 14,009 | 2 | BMD | Catheter related bloodstream infections (BSI) | ||||
Castanheira [29] | 2006 | 2008 | North America | 4873 | 4288 | 2251 | 585 | 1 | 1 | 4 | BMD | Bloodstream infections, Skin and soft tissue infections, Pneumonia |
Morrissey [76] | 2011 | 2012 | Italy | 82 | 41 | 41 | 41 | 2 | BMD | Bacteraemia | ||
Morrissey [76] | 2011 | 2012 | Spain | 79 | 45 | 45 | 34 | 1 | Bacteraemia | |||
Cui [31] | 2009–2010 | 2013 | China | 713 | 713 | 4 | Agar dilution | Blood | ||||
Song [106] | 2013–2014 | 2017 | China | 1104 | 1104 | 3 | Agar dilution | Blood | ||||
Pedroso [78] | 2008–2009 | 2018 | Brazil | 58 | 58 | 1 | Automated VITEK-2 system | Blood | ||||
Li [67] | 2014 | 2016 | China | 1798 | 1499 | 632 | 299 | 2 | BMD | Pneumonia, Skin and soft tissue infection, Blood infection | ||
Isnard [53] | 2011–2014 | 2018 | France | 200 | 100 | 19 | 100 | 2 | BMD | Prosthetic joint infections | ||
Gandra [47] | 2008–2014 | 2016 | India | 5426 | 1089 | 608 | 4337 | 17 | 21 | BMD | Blood | |
Draghi [36] | 2004 | 2005 | USA | 3368 | 2872 | 1556 | 496 | 1 | BMD | Skin, Blood, Respiratory tract | ||
Jones [61] | 2007 | 2009 | Italy | 151 | 98 | 53 | 2 | BMD | Blood | |||
Mutnick [77] | 2001–2002 | 2003 | USA | 5848 | 4677 | 1171 | 1 | BMD | Blood, Skin, Respiratory and Urinary tract | |||
Jones [62] | 2008 | 2009 | Italy | 128 | 59 | 69 | 2 | BMD | Medical centers | |||
Jones [62] | 2008 | 2009 | France | 140 | 100 | 40 | 1 | BMD | Medical centers | |||
Martinez [70] | 2006 | 2013 | Mexico | 142 | 142 | 5 | BMD | Blood | ||||
Zhanel [116] | 2005–2006 | 2008 | Canada | 1046 | 162 | 2 | Blood, urine, Wound/tissue, Respiratory specimens |