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Table 2 Characteristics and antibiotic resistance profile of the Gram–negative multidrug-resistant organisms

From: Poor infection prevention and control standards are associated with environmental contamination with carbapenemase-producing Enterobacterales and other multidrug-resistant bacteria in Swiss companion animal clinics

Insti-tutionSpeciesRepresen-tative strainOrigin (n=)STβ-lactamase genesAntibiotic resistance profilea
SMX
(≥512)
TMP
(>4)
CIP
(>0.5)
TET
(≥16)
MERO
(>8)
(ESBL screen >0.125)
AZI
NAb
NAL
(≥32)
FOT
(>2)
(ESBL screen >1)
CHL
(>8)
TGC
(>2)
TAZ
(>4)
(ESBL screen >1)
COL
(>2)
AMP
(>8)
GEN
(>4)
EnvEmpl
AE. coliM_054 173 32≤0.25≤0.015≤2≤0.034≤4≤0.25≤8≤0.25≤0.5164≤0.5
E. coliM_042 1543 32≤0.25≤0.015≤2≤0.03≤2≤4≤0.25≤8≤0.25≤0.51642
E. coliM_064 12640 32≤0.25≤0.015≤2≤0.034≤4≤0.25≤8≤0.25≤0.582≤0.5
E. coliM_054 11193CTX-M-1516≤0.25>8≤2≤0.034>128>4≤8≤0.254≤1>6416
E. coliM_050 1167NDM-5/ CMY-2/TEM-30>1024>32>8>64>16>64>128>4>128≤0.25>8≤1>6432
E. coliM_018 1131CTX-M-15320.50.254≤0.034>128>4≤8≤0.25>8≤1>64≤0.5
E. coliM_104 195CTX-M-55320.5≤0.015≤2≤0.034≤4>4≤8≤0.258≤1>64≤0.5
E. cloacae19/EPI01541   >10240.50.5>640.2532321≤80.51≤1>644
BK. pneumoniae19/EPI007718 11OXA-48/ DHA-1>10244>841>64>128>4320.5>8≤1>644
E. coli19/EPI00831 410OXA-181/ CMY-42162>8>640.516>128>4321>8≤1>64≤0.5
E. coliMB_042 1410OXA-181/ CMY-42161>840.58>128>4≤8≤0.25>8≤1>64≤0.5
E. coli19/EPI00601 4038OXA-48>1024>32>8>640.516>128>4161>8≤1>64≤0.5
E. coliMB_091 1538 32≤0.25≤0.015≤2≤0.03≤2≤4≤0.25≤8≤0.25≤0.5>164≤0.5
E. coliMB_066 195 16≤0.25≤0.015≤2≤0.03≤2≤4≤0.25≤8≤0.25≤0.582≤0.5
E. coliMB_100 1335 16≤0.25≤0.015≤2≤0.034≤4≤0.25≤8≤0.25≤0.542≤0.5
E. coliMB_003 11730CTX-M-1>1024>32≤0.015≤2≤0.038≤4>4>128≤0.251≤1>64>32
E. coliMB_074 1131CTX-M-27>1024≤0.25>864≤0.03≤2>128>4≤8≤0.254≤1>641
E. coliMB_073 1131CTX-M-1432≤0.25≤0.015≤20.068≤4>4≤8≤0.252≤1>64≤0.5
E. cloacae19/EPI00601  OXA-48≤81≤0.015≤20.516≤42≤8≤0.25≤0.5≤1>64≤0.5
E. cloacae19/EPI00591   >1024>322>640.128>128>4>128≤0.25>8≤1>644
CE. coliMC_022 169 32≤0.25≤0.015< 2≤0.034≤4≤0.25≤8≤0.25≤0.584≤0.5
EE. coli19/EPI01551  OXA-48>1024>32>8>640.258>128>4>128≤0.25>8≤1>64≤0.5
  1. aMIC in bold indicates resistance. The resistance breakpoints presented are those for E. coli from the European Committee on Antimicrobial Susceptibility Testing [32] except for NAL, SMX and TET for which the breakpoints from the Clinical and Laboratory Standards Institute [33] were used. bNA, not available; no breakpoints were available for E. coli for azithromycin; an MIC > 64 was tentatively used as resistance breakpoint. Abbreviations: Env environment; Empl employee, ST sequence type, SMX sulfamethoxazole, TMP trimethoprim, CIP ciprofloxacin, TET tetracycline, MERO meropenem, AZI azithromycin, NAL nalidixic acid, FOT cefotaxime, CHL chloramphenicol, TGC tigecycline, TAZ ceftazidime, COL colistin, AMP ampicillin, GEN gentamicin, E. coli Escherichia coli, E. cloacae Enterobacter cloacae, K. pneumoniae Klebsiella pneumoniae