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Table 5 Mortality due to sepsis and blood culture results

From: Sepsis related mortality of extremely low gestational age newborns after the introduction of colonization screening for multi-drug resistant organisms

Exposure

N exposed

Mortality due to sepsis [%]

Odds ratio* (95% CI)

p*

Gestational age [OR per additional week]

12.823

2.2

0.7 (0.66–0.75)

< 0.001

Discharge 2014–2018

8.903

2.1

0.9 (0.73–1.23)

0.69

Female sex

5.950

1.8

0.7 (0.58–0.95)

0.02

Multiple birth

3.979

2.0

0.9 (0.70–1.22)

0.59

SGA

1.753

4.1

2.0 (1.49–2.58)

< 0.001

All blood cultures negative*

10.893

1.5

Ref.

 

Staph. epidermidis

745

2.4

1.2 (0.7–2.0)

0.74

Staph. haemolyticus

196

5.1

2.6 (1.3–5.0)

0.005

E coli

169

11.2

7.3 (4.3–12)

< 0.001

Staph. aureus

150

4.0

2.3 (1.00–5.3)

0.053

Staph. capitis

105

0

 

Enterococci, no VRE

97

8.2

4.2 (2.0–9.0)

< 0.001

Enterobacter spp.

94

6.4

3.4 (1.4–7.9)

0.005

Group B Strep.

86

9.3

5.5 (2.6–12)

< 0.001

Klebsiella, no MDRO

75

10.7

5.6 (2.6–12)

< 0.001

Candida spp

45

26.7

16 (7.9–32)

< 0.001

E. coli ESBL

32

12.5

6.7 (2.3–20)

0.001

Staph. hominis

28

7.1

4.0 (0.9–17)

0.06

Enterococci, VRE

20

5.0

2.8 (0.4–21)

0.33

Serratia

17

5.9

2.9 (0.4–23)

0.30

Klebsiella ESBL

16

0

 

MRSA

16

6.3

3.7 (0.5–28)

0.21

Pseudomonas

14

57.1

59 (19–180)

< 0.001

Other streptococci

12

0

 

Listeria

8

12.5

11 (1.3–92)

0.04

Pneumococci

3

0

 

Proteus

1

0

 

Bacteroides

1

0

 
  1. *Logistic regression, result of last positive blood culture before death or discharge was entered as category variable with all blood-culture negative infants as reference