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Table 1 Baseline and Procedural Characteristics, by Surgical Antimicrobial Prophylaxis Administration (Before Incision / After Cord Clamping)

From: Antimicrobial prophylaxis administration after umbilical cord clamping in cesarean section and the risk of surgical site infection: a cohort study with 55,901 patients

  Before incision After cord clamping p
n 26,405 29,496  
Age (%)    0.043
 < 30 years 7891 (29.9) 8902 (30.2)  
 30–40 years 16,631 (63.0) 18,346 (62.2)  
 > 40 years 1883 (7.1) 2248 (7.6)  
BMI in kg/m2, median [IQR])a 28.0 [25.2, 31.6] 27.3 [24.2, 30.9] < 0.001
SAP agent (%)    < 0.001
 Amoxicillin + Clavulanate 3601 (13.6) 1770 (6.0)  
 Cefazolin 9081 (34.4) 9073 (30.8)  
 Ceftriaxone 782 (3.0) 5117 (17.3)  
 Cefuroxime 12,941 (49.0) 13,536 (45.9)  
Minutes between SAP administration and incision −15 [−25, −9] 10 [5, 15] < 0.001
Elective surgery = yes (%) 13,458 (51.0) 14,820 (50.2) 0.089
ASA Score (%)    < 0.001
 ASA 1 4427 (16.8) 6862 (23.3)  
 ASA 2 20,229 (76.6) 20,648 (70.0)  
 ASA 3/4/5 1401 (5.3) 1514 (5.1)  
 NA 348 (1.3) 472 (1.6)  
Contaminated wound = yes (%) 5724 (21.7) 6440 (21.8) 0.663
Procedure duration in minutes (median [IQR])b 38 [29, 49] 37 [29, 48] < 0.001
Hospital bed size (%)    < 0.001
 < 200 12,328 (46.7) 17,588 (59.6)  
 200–499 11,497 (43.5) 5757 (19.5)  
 500+ 2580 (9.8) 6151 (20.9)  
Procedure after January 1, 2014 = yes (%) 18,081 (68.5) 9612 (32.6) < 0.001
  1. Abbreviations
  2. ASA American Society of Anesthesiologists
  3. BMI Body mass index
  4. IQR Interquartile range
  5. SAP Surgical antimicrobial prophylaxis
  6. aBMI NA: Before =15′510 (58.7%); After = 18′052 (61.2%)
  7. bDuration NA: Before =144 (0.5%); After = 94 (0.3%)