Univariable analysis | Multivariable analysis | |||||
---|---|---|---|---|---|---|
OR | (95% CI) | p value | OR | (95% CI) | p value | |
Year of sampling (per 1 year increase) | ||||||
2014–2018 | 0.84 | (0.77–0.91) | < 0.001 | 0.85 | (0.79–0.93) | < 0.001 |
Care setting type | ||||||
Outpatient clinics | 1 | – | – | 1 | – | – |
Secondary care hospitals | 3.91 | (2.40–6.39) | < 0.001 | 3.59 | (2.44–5.27) | < 0.001 |
Tertiary care hospitals | 4.74 | (2.31–9.74) | < 0.001 | 5.41 | (2.93–9.99) | < 0.001 |
Specialist care hospitals | 5.85 | (3.23–10.61) | < 0.001 | 7.24 | (3.90–13.43) | < 0.001 |
Prevention and rehabilitation care centres | 7.21 | (3.21–16.17) | < 0.001 | 9.58 | (3.02–30.32) | < 0.001 |
Other hospitals | 0.66 | (0.11–4.17) | 0.661 | –* | –* | –* |
German region | ||||||
Northeast | 0.37 | (0.19–0.73) | 0.004 | 0.25 | (0.12–0.51) | < 0.001 |
Southeast | 0.32 | (0.17–0.61) | < 0.001 | 0.20 | (0.11–0.36) | < 0.001 |
Southwest | 0.42 | (0.22–0.80) | 0.008 | 0.31 | (0.18–0.52) | < 0.001 |
West | 1 | – | – | 1 | – | – |
Northwest | 0.94 | (0.33–2.66) | 0.905 | 0.72 | (0.37–1.40) | 0.338 |
Patient gender | ||||||
Female | 1 | – | – | 1 | – | – |
Male | 2.19 | (1.70–2.84) | < 0.001 | 1.91 | (1.55–2.36) | < 0.001 |
Patient age | ||||||
< 1 year | 0.08 | (0.03–0.19) | < 0.001 | 0.06 | (0.03–0.14) | < 0.001 |
1–19 years | 0.20 | (0.13–0.30) | < 0.001 | 0.21 | (0.17–0.38) | < 0.001 |
20–39 years | 1.17 | (0.84–1.63) | 0.359 | 1.56 | (1.10–2.23) | 0.014 |
40–59 years | 1 | – | – | 1 | – | – |
60–79 years | 0.92 | (0.73–1.17) | 0.487 | 0.96 | (0.73–1.26) | 0.775 |
80 ≥ years | 0.31 | (0.23–0.42) | < 0.001 | 0.37 | (0.28–0.49) | < 0.001 |
Clinical specimen material | ||||||
Upper respiratory | 1 | – | – | 1 | – | – |
Lower respiratory | 3.07 | (2.45–3.84) | < 0.001 | 1.52 | (1.21–1.91) | < 0.001 |
Other respiratory | 2.42 | (1.42–4.13) | 0.001 | 1.52 | (0.95–2.43) | 0.081 |
Blood | 2.10 | (1.32–3.34) | 0.002 | 1.25 | (0.91–1.73) | 0.167 |
Wound | 0.68 | (0.52–0.90) | 0.007 | 0.44 | (0.33–0.59) | < 0.001 |
Urine | 0.55 | (0.43–0.71) | < 0.001 | 0.37 | (0.27–0.51) | < 0.001 |
Other | 1.13 | (0.88–1.44) | 0.345 | 0.89 | (0.70–1.12) | 0.317 |