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Table 4 Most common clinical conditions with the main pathogens and their antimicrobial resistance profile, Ethiopia

From: Prevalence of antimicrobial resistance and its clinical implications in Ethiopia: a systematic review

Clinical condition

Most frequently isolated pathogens

Antimicrobial profile: total isolates (% resistance)

TSX

AMP

AMC

AMC-ClA

CIP

CRO

GCN

CLO

NOR

OX/MET

CARBS

Urinary tract infection

E. coli

1009 (60)

898 (87)

222 (83)

484 (46)

845 (28)

84 (35)

1210 (28)

650 (41)

268 (22)

–

–

 

K. pneumoniae

92 (52)

131 (92)

24 (88)

83 (48)

120 (31)

86 (24)

111 (38)

65 (54)

38 (42)

–

–

 

P. aeruginosa

63 (70)

48 (75)

18 (78)

14 (79)

126 (12)

43 (42)

115 (24)

36 (56)

54 (20)

–

–

 

S. aureus

171 (73)

192 (71)

166 (80)

66 (59)

56 (43)

119 (61)

169 (53)

37 (68)

11 (73)

–

–

Diarrhea

E. coli

348 (75)

348 (83)

47(11)

541(47)

348 (6)

108(6)

348(30)

348(26)

240(9)

–

–

 

Salmonella Spp

116 (16)

102(6)

39 (74)

155 (12)

234 (8)

195 (5)

214 (8)

234 (13)

70 (3)

91 (51)

–

 

Shigella Spp

127 (51)

103 (85)

99 (83)

66 (20)

129 (13)

58(16)

 

158 (44)

122 (5)

–

–

 

Campylobacter

102 (53)

119 (57)

20 (80)

44 (36)

119 (14)

64 (16)

102 (26)

102 (17)

82 (12)

–

–

Surgical site Infection

S. aureus

171 (73)

192 (71)

266 (80)

66 (59)

56 (43)

119 (61)

169 (53)

37 (68)

11 (72)

80 (85)

22 (9)

 

E. coli

60 (73)

90 (90)

35 (74)

61(97)

90 (43)

90 (62)

84 (55)

64 (39)

9 (44)

–

12 (0)

 

K. pneumoniae

44 (80)

83 (96)

43 (100)

69 (84)

83 (33)

83 (70)

83 (47)

40 (60)

–

–

–

 

P. aeruginosa

15 (53)

32 (100)

17 (100)

26 (100)

32 (59)

32 (94)

21 (52)

20 (80)

5 (20)

20 (55)

–

Sepsis

S. aureus

98 (47)

91 (58)

–

20 (0)

98 (18)

82 (23)

98 (33)

91 (25)

–

–

–

 

E. coli

47 (60)

31 (68)

–

29 (41)

47 (21)

29 (38)

47 (83)

31 (32)

–

–

–

 

K. pneumoniae

19 (42)

19 (94)

–

19 (32)

19 (16)

19 (79)

19 (16)

31.58

–

–

–

Pneumonia

S. pneumoniae

77 (58)

60 (45)

–

–

 

60 (8)

1 (0)

77 (6)

–

–

–

 

K. pneumoniae

29 (45)

3 (100)

3 (100)

33 (9)

29 (7)

59 (54)

59 (64)

29 (17)

–

–

–

 

S. aureus

42 (52)

24 (92)

–

–

18 (11)

24 (88)

18 (17)

42 (17)

–

–

–

 

E. coli

19 (32)

10 (90)

3 (0)

13 (15)

26 (8)

29 (38)

29 (31)

19 (0)

–

–

–

Middle ear infections

S. aureus

–

–

–

46 (61)

–

–

–

54 (26)

–

55 (35)

–

 

Proteus spp.

227 (63)

227 (75)

–

119 (78)

–

–

283 (64)

227 (37)

227 (31)

–

–

 

P. aeruginosa

 

88 (90)

–

28 (89)

–

–

–

18 (78)

–

–

–

 

Klebsiella spp.

89 (66)

51 (82)

–

–

–

–

–

43 (51)

30 (40)

–

–

 

E. coli

–

7 (86)

6 (50)

–

–

–

–

7.1

–

–

–

Nosocomial infections

S. aureus

77 (35)

–

77 (51)

77 (23)

87 (21)

87 (18)

87 (16)

87 (24)

–

–

–

 

E. coli

67 (33)

–

33 (64)

33 (55)

42 (31)

42 (38)

42 (33)

42 (36)

–

–

–

 

Citrobacter spp.

48 (29)

–

29 (76)

29 (55)

33 (12)

33 (45)

33 (40)

33 (33)

–

–

–

 

Klebsiella spp.

47 (15)

–

15 (87)

15 (67)

15 (27)

15 (47)

15 (33)

15 (27)

–

–

–

  1. The first number indicates the total number of resistant isolates for the specific pathogen and medication, and the number in the bracket is percent of resistant isolates
  2. TSX, trimethoprim-sulfamethoxazole; AMP, ampicillin; AMC, amoxicillin; AMC-CIA, amoxicillin-clavulanic acid; CIP, ciprofloxacin; CRO, ceftriaxone; GCN, gentamicin; CLO, chloramphenicol; NOR, norfloxacin; OX/MET, oxacillin and or methicillin; CARBS, carbapenems (imipenem and or meropenem)