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Table 4 Regression analysis between antibiotic consumption and the incidence of HO-CDI with 1-month interval matching

From: Correlation between antibiotic consumption and the incidence of healthcare facility-onset Clostridioides difficile infection: a retrospective chart review and analysis

Risk factor

Univariate analysisa

Multivariate analysisc

Coefficientb

P value

Coefficient

P value

DDD

 BLBLIs

0.07

0.10

  

 Glycopeptides

− 0.16

0.04

− 0.16

0.04

DOT

 BLBLIs

0.07

0.045

  

 Glycopeptides

− 0.20

0.02

− 0.20

0.02

 Clindamycin

− 0.21

0.07

  
  1. BLBLIs β-lactam/β-lactam inhibitors, DDD defined daily dose, DOT days of therapy, HO-CDI healthcare facility-onset C. difficile infection
  2. aVariables with P < 0.1 in the univariate analysis were included in the multivariate analysis
  3. bChanges in the incidence of HO-CDI according to antibiotic consumption
  4. cR-squared in multivariate analysis: 0.19 [DDD] and 0.22 [DOT]
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Antimicrobial Resistance & Infection Control

ISSN: 2047-2994

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