Table 4 Mean cost of preventive measures between periods per year and mean cost of SSI-CRAN between periods per year

Mean cost of preventive measures between periods

 Pre-care bundle period^a

  Systemic antibiotic prophylaxis:   Cefuroxime 1.5 g

2.6

5.2

1029.6

  Sterile impermeable drape

0.3

0.3

59.4

  Total cost

2.9

5.5

1089

 Care bundle period^a

  Systemic antibiotic prophylaxis: cefuroxime 1.5 g

2.6

5.2

1097.2

  Topical antibiotic prophylaxis: vancomycin 1 g

6.9

6.9

1455.9

  Sterile absorbent drape

0.6

2.6

548.6

  Total cost

10.1

14.7

3101.7

Mean cost of SSI-CRAN between periods

Pre-care bundle period

714,886

1089

715,975

Care bundle period

212,029

3101.7

215,130.7

Difference of cost between periods

–

–

500,844.3