Table 2 The susceptibility and resistance trends of Gram-negative pathogens to antimicrobial agents

E. coli

MDR

9944

–

–

71.4

–

76.2

–

65.8

–

72.1

–

ESBL-E. coli

9944

–

–

53.4

–

61.2

–

55.6

–

55.9

–

CR-E. coli

9944

–

–

1.5

–

1.2

–

2.0

–

1.1

–

amoxicillin

9944

128

256

74.8

20.4

93.2

5.1

83.4

15.8

84.9

14.4

amoxicillin/clavulanic acid

9944

16

256

39.3

40.6

26.9

40.6

14.6

60.7

18.0

56.4

piperacillin/tazobactam

9944

2

64

7.5

86.4

12.3

78.0

8.1

88.3

6.7

89.1

cefoperazone/sulbactam^a

9944

4

32

8.5

80.6

15.3

65.5

9.3

76.5

8.0

79.5

ceftazidime/avibactam

3683

0.25

1

1.0

99.0

–

–

–

–

–

–

cefazolin

9944

128

128

59.7

34.8

69.1

26.7

62.6

30.7

63.5

29.8

cefuroxime

9944

128

128

55.0

41.5

64.8

31.8

58.7

40.1

59.9

37.4

ceftazidime

9944

1

64

28.9

63.2

33.9

58.7

30.6

62.3

30.9

61.9

ceftriaxone

9944

16

64

55.8

43.8

65.8

33.7

57.8

41.9

59.6

40.3

cefepime

9944

1

32

21.0

58.4

30.2

46.7

24.4

54.1

25.8

51.7

cefoxitin

9944

4

32

13.6

77.6

19.5

69.4

13.5

80.4

13.9

74.6

moxalactam

9943

0.25

2

2.5

95.6

3.0

93.9

2.3

94.4

2.6

94.9

aztreonam

9944

4

64

36.2

55.6

42.2

49.5

37.5

54.8

37.6

53.6

ertapenem

5495

0.016

0.064

1.5

97.9

–

–

–

–

–

–

imipenem

9944

0.125

0.5

1.4

98.3

1.0

97.8

1.4

98.1

1.1

98.7

meropenem

9944

0.016

0.064

1.4

98.5

1.2

98.7

1.5

98.2

1.1

98.7

amikacin

9944

4

8

2.9

96.7

4.9

93.8

3.3

96.3

3.6

95.5

gentamicin

9944

4

128

39.5

58.7

44.0

51.9

39.9

57.1

43.3

53.6

ciprofloxacin

9944

4

32

64.3

26.0

65.7

27.0

58.9

30.9

74.0

17.9

levofloxacin

9944

4

32

53.3

37.1

61.7

31.6

53.1

37.2

57.5

34.3

trimethoprim/sulfamethoxazole

9944

8

8

57.1

42.9

60.8

39.2

58.3

41.7

58.7

41.3

fosfomycin

9944

0.5

4

1.7

95.2

0.1

93.2

0.2

95.5

0.6

94.5

polymyxin B

9944

0.5

2

2.2

97.8

1.5

98.5

1.4

98.6

7.2

92.8

tigecycline

9944

0.25

0.5

0

100

0

99.6

0

100

0

100

K. pneumoniae

MDR

4378

–

–

38.7

–

30.6

–

32.6

–

36.1

–

ESBL-K. pneumoniae

4378

–

–

32.5

–

30.6

–

30.8

–

30.9

–

CR-K. pneumoniae

4378

–

–

18.3

–

7.0

–

11.7

–

13.6

–

amoxicillin/clavulanic acid

3679

8

128

36.0

52.4

29.7

45.4

21.4

67.7

32.5

56.7

piperacillin/tazobactam

4378

4

128

22.0

70.5

14.0

81.2

15.5

79.5

20.1

75.5

cefoperazone/sulbactam^a

4378

1

128

24.9

69.7

14.4

76.9

19.4

73.9

22.3

71.5

ceftazidime/avibactam

1655

0.5

4

1.6

98.4

–

–

–

–

–

–

cefazolin

4378

2

128

43.5

52.5

40.6

55.9

40.2

55.1

43.3

50.4

cefuroxime

4378

8

128

42.7

54.7

37.1

61.1

37.5

59.5

43.1

54.7

ceftazidime

4378

0.5

64

31.6

64.9

20.1

73.8

27.0

69.8

30.9

64.8

ceftriaxone

4378

0.125

64

40.2

59.3

34.5

65.5

37.5

62.2

39.5

60.0

cefepime

4378

0.125

64

27

64.8

16.2

72.9

20.8

70.7

26.5

65.5

cefoxitin

4378

4

128

27.3

68.6

22.3

75.5

20.5

73.6

25.5

70.1

moxalactam

4378

0.5

128

17.4

80.3

6.6

92.1

10.0

87.1

14.3

83

aztreonam

4378

0.125

64

34.1

63.7

24.0

72.9

29.0

70.4

32.5

65.5

ertapenem

2518

0.016

32

20.5

78.6

–

–

–

–

–

–

imipenem

4378

0.25

32

17.5

81.6

5.2

93.9

9.7

88.9

13.2

86.0

meropenem

4378

0.032

32

17.4

82.2

5.7

93.4

9.7

89.1

12.6

86.8

amikacin

4378

2

128

13.7

86.2

6.1

93.9

9.1

90.9

12.2

87.5

gentamicin

4378

1

128

26.8

72.4

20.1

78.6

21.1

78.0

26.5

72.6

ciprofloxacin

4378

0.25

32

44.5

51.7

36.7

58.5

40.2

56.3

43.3

50.4

levofloxacin

4378

0.25

32

34.1

55.8

25.3

60.7

26.1

61.9

31.4

58.0

trimethoprim/sulfamethoxazole

4378

0.125

8

36.8

63.2

31.9

68.1

35.8

64.2

32.5

67.5

fosfomycin

4378

4

128

6.1

89.6

0.4

90.8

0.6

90.0

2.9

91.7

polymyxin B

4378

1

2

3.6

96.4

0.9

99.1

1.5

98.5

5.7

94.3

tigecycline

4378

0.5

1

0.2

98.9

0.9

95.2

1.5

97.4

0.1

99.1

E. cloacae

MDR

–

–

–

20.8

–

24.6

28.9

23.8

piperacillin/tazobactam

785

2

128

13.1

78.5

9.2

84.6

11.8

80.3

14.6

76.9

cefoperazone/sulbactam^a

785

0.5

32

9.8

80.4

7.7

83.1

15.8

75.0

8.5

76.9

ceftazidime/avibactam

265

0.25

4

6.0

94.0

–

–

–

–

–

–

ceftazidime

785

0.25

64

29.6

67.5

27.7

69.2

23.7

72.4

28.5

69.2

ceftriaxone

785

0.25

64

39.9

59.5

52.3

46.2

42.1

57.9

40.8

59.2

cefepime

785

0.125

16

13.4

78.7

6.2

84.6

13.2

81.6

12.3

75.4

moxalactam

785

0.25

32

6.2

84.2

3.1

86.2

5.3

81.6

6.9

83.1

aztreonam

785

0.125

64

29.7

68.4

27.7

67.7

25.0

75.0

29.2

69.2

ertapenem

423

0.016

0.5

5.4

92.4

–

–

–

–

–

–

imipenem

785

0.25

1

4.8

93.0

1.5

90.8

5.3

92.1

4.6

92.3

meropenem

785

0.032

0.125

4.5

94.6

0

98.5

3.9

94.7

4.6

91.5

amikacin

785

2

4

2.3

97.3

4.6

95.4

1.3

98.7

3.8

95.4

gentamicin

785

1

64

14.5

81.7

12.3

83.1

11.8

77.6

13.8

83.8

ciprofloxacin

785

0.064

16

25.0

69.3

24.6

63.1

26.3

69.7

25.4

67.7

levofloxacin

785

0.064

8

17.7

73.8

23.1

69.2

21.1

69.7

17.7

73.8

trimethoprim/sulfamethoxazole

785

0.125

8

25.1

74.9

41.5

58.5

31.6

68.4

19.2

80.8

fosfomycin

785

8

64

1.1

93.2

0

84.6

0

90.8

0.8

93.8

polymyxin B

785

1

32

28.7

71.3

1.5

98.5

0

100

20.0

80.0

tigecycline

785

0.25

1

0.8

98.2

1.5

98.5

0.5

98.2

2.3

96.9

Klebsiella spp

MDR

401

–

–

20.0

–

44.4

21.9

35.4

Piperacillin/tazobactam

401

1

128

15.5

79.3

33.3

63.0

9.4

90.6

19.0

78.5

Cefoperazone/Sulbactam^a

401

4

128

18.0

74.1

14.8

77.8

9.4

84.4

12.7

74.7

Ceftazidime/avibactam

130

0.25

4

4.6

95.4

–

–

–

–

–

–

Cefazolin

198

4

128

43.9

37.9

72.7

18.2

40.9

45.5

60.5

32.6

Cefuroxime

266

8

128

38.0

58.3

59.3

37.0

31.2

62.5

62.8

34.9

Ceftazidime

401

0.5

64

28.7

68.3

37.0

48.1

18.8

81.2

32.9

64.6

Ceftriaxone

401

0.25

64

39.4

58.9

63.0

37.0

25.0

75.0

50.6

48.1

Cefepime

401

0.125

16

15.0

79.1

18.5

63.0

12.5

81.2

22.8

68.4

Cefoxitin

198

4

128

18.2

76.8

54.5

45.5

18.2

81.8

16.3

76.7

Moxalactam

400

0.25

16

7.5

88.5

7.4

88.9

3.1

93.8

6.3

89.9

Aztreonam

401

0.25

64

28.7

67.8

51.9

37.0

21.9

78.1

31.6

62.0

Ertapenem

204

0.016

1

7.4

89.2

–

–

–

–

–

–

Imipenem

401

0.25

2

6.2

89.8

3.7

88.9

3.1

96.9

5.1

89.9

Meropenem

401

0.032

0.25

5.0

94.0

0

100

3.1

96.9

3.8

93.7

Amikacin

401

2

8

2.5

97.3

7.4

92.6

3.1

96.9

3.8

94.9

Gentamicin

401

1

64

12.0

86.0

14.8

85.2

12.5

78.1

26.6

70.9

Ciprofloxacin

401

0.064

32

30.2

67.3

48.1

48.1

31.2

68.8

49.4

49.4

Levofloxacin

401

0.125

8

21.2

72.1

44.4

51.9

21.9

68.8

30.4

58.2

Trimethoprim/Sulfamethoxazole

401

0.125

8

19.0

81.0

37.0

63.0

31.2

68.8

27.8

72.2

Fosfomycin

401

4

64

2.5

93.5

0

92.6

0

84.4

2.5

93.7

Polymyxin B

401

1

2

6.0

94.0

0

100

0

100

5.1

94.9

Tigecycline

401

0.25

1

1.2

97.8

7.4

92.6

6.2

93.8

1.3

96.2

Salmonella spp

MDR

–

–

–

45.1

–

36.4

–

29.4

–

38.7

–

Amoxicillin

384

128

256

57.6

40.6

57.6

39.4

50.0

50.0

37.1

59.7

Amoxicillin/Clavulanic Acid

384

8

128

7.6

91.6

8.2

57.6

5.9

82.4

4.5

35.5

Piperacillin/Tazobactam

384

1

16

1.6

95.8

0

87.9

5.9

100

1.6

100

Cefoperazone/Sulbactam^a

384

2

8

2.1

95.8

9.1

90.9

0

94.1

0

98.4

Ceftazidime/Avibactam

117

0.5

0.5

0

100

–

–

–

–

–

–

Ceftazidime

384

0.25

4

9.9

90.1

12.1

87.9

8.8

91.2

4.8

95.2

Ceftriaxone

384

0.125

16

10.9

88.8

15.2

84.8

5.9

91.2

6.5

93.5

Cefepime

384

0.125

1

5.7

91.4

0

90.9

2.9

97.1

6.5

93.5

Moxalactam

384

0.25

8

1.0

95.6

0

100

0

94.1

1.6

93.5

Aztreonam

384

0.125

8

6.2

84.9

12.1

84.8

2.9

97.1

1.6

74.2

Ertapenem

201

0.008

0.016

0.5

99.5

–

–

–

–

–

–

Imipenem

384

0.064

0.25

0.3

99.2

0

100

0

97.1

0

100

Meropenem

384

0.032

0.125

1.6

96.4

3.0

97.0

0

100

1.1

91.9

Amikacin

384

2

8

1.0

98.7

3.0

97.0

0

100

0

100

Gentamicin

384

1

4

7.3

91.9

9.1

90.9

2.9

97.1

6.5

93.5

Ciprofloxacin

384

0.5

1

18

29.7

18.2

36.4

14.7

35.3

25.8

17.7

Levofloxacin

384

0.25

1

8.6

33.1

6.1

33.3

5.9

32.4

3.2

30.6

Trimethoprim/Sulfamethoxazole

384

0.125

8

13.8

86.2

15.2

84.8

11.8

88.2

4.8

95.2

Fosfomycin

384

0.5

4

0.5

99.0

0

97.0

0

100

0

100

Polymyxin B

384

2

16

38.3

61.7

0

100

0

100

37.1

62.9

Tigecycline

384

0.25

1

1.3

97.4

0

100

2.9

97.1

0

91.9

Serratia spp

MDR

–

–

–

9.3

–

37.5

–

10.3

–

11.9

–

Piperacillin/Tazobactam

313

1

64

6.4

87.2

25.0

75.0

6.9

82.8

6.0

85.1

Cefoperazone/Sulbactam^a

312

1

64

16.0

75.6

25.0

50.0

17.2

72.4

4.5

82.1

Ceftazidime/Avibactam

83

0.125

0.25

0

100

–

–

–

–

–

–

Ceftazidime

311

0.25

8

9.6

89.1

37.5

62.5

6.9

89.7

10.4

88.1

Ceftriaxone

312

0.125

64

28.8

71.2

37.5

62.5

31.0

69.0

25.4

74.6

Cefepime

313

0.125

16

18.5

74.8

25.0

75.0

20.7

72.4

11.9

80.6

Moxalactam

312

0.5

4

3.2

94.9

12.5

87.5

0

100

1.5

94.0

Aztreonam

313

0.125

32

16.0

72.8

25.0

75.0

24.1

75.9

19.4

76.1

Ertapenem

169

0.016

0.064

5.3

94.1

–

–

–

–

–

–

Imipenem

313

0.5

2

7.0

89.1

37.5

62.5

3.4

96.6

3.0

94.0

Meropenem

313

0.064

0.25

5.1

93.0

25.0

75.0

0

96.6

1.5

94.0

Amikacin

313

4

16

1.0

98.4

0

100

0

100

0

97.0

Gentamicin

313

2

128

20.1

79.2

25.0

62.5

20.7

79.3

19.4

79.1

Ciprofloxacin

312

0.25

16

30.4

50.0

25.0

50.0

31.0

69.0

29.9

47.8

Levofloxacin

313

0.5

16

25.9

68.1

25.0

62.5

20.7

75.9

25.4

70.1

Trimethoprim/Sulfamethoxazole

313

0.125

0.5

6.1

93.9

37.5

62.5

10.3

89.7

11.9

88.1

Fosfomycin

312

4

8

0.6

98.7

0

100

0

100

0

100

Tigecycline

312

0.5

2

1.5

97.5

7.5

92.5

1.7

98.3

1.5

98.5

E. coli

MDR

71.2

–

71.1

–

71.8

–

–

0.749

ESBL-E. coli

55.4

–

50.4

–

51.0

–

↓

0.000

CR-E. coli

1.2

–

1.3

–

1.7

–

–

0.397

amoxicillin

85.6

13.9

84.6

14.5

83.4

15.0

↓

0.000

amoxicillin/clavulanic acid

19.7

51.5

24.2

48.7

44.0

38.1

↑

0.000

piperacillin/tazobactam

6.2

89.0

5.6

82.5

8.1

83.0

–

0.04

cefoperazone/sulbactam^a

8.7

80.7

7.0

91.1

7.8

84.0

↓

0.000

ceftazidime/avibactam

–

–

–

–

1.0

99.0

–

NA

cefazolin

61.8

31.2

57.1

37.0

56.1

39.6

↑

0.000

cefuroxime

50.6

45.4

53.6

43.0

52.7

43.1

↓

0.000

ceftazidime

28.9

62.6

25.6

65.8

28.2

63.7

↓

0.000

ceftriaxone

57.3

42.1

53.5

46.0

52.6

47.2

↓

0.000

cefepime

24.9

52.4

20.6

58.5

15.3

66.6

↓

0.000

cefoxitin

17.0

74.4

9.5

82.9

13.1

78.1

↓

0.000

moxalactam

2.5

95.5

2.3

96.8

2.5

95.9

–

0.661

aztreonam

34.9

54.8

30.9

59.8

37.3

55.9

↓

0.021

ertapenem

–

–

1.3

98.2

1.7

97.7

–

0.281

imipenem

1.2

98.4

1.3

98.5

1.6

98.2

–

0.140

meropenem

1.0

98.6

1.3

98.6

1.6

98.4

–

0.217

amikacin

3.1

96.3

2.5

97.2

2.3

97.7

↓

0.000

gentamicin

43.5

54.0

40.9

58.1

34.9

64.4

↓

0.000

ciprofloxacin

64.5

24.4

66.3

25.1

60.5

28.9

↓

0.000

levofloxacin

54.4

36.0

51.1

38.4

50.9

38.9

↓

0.000

trimethoprim/sulfamethoxazole

60.3

39.7

57.7

42.3

54.0

46.0

↓

0.000

fosfomycin

0.4

95.1

2.2

95.4

3.1

95.7

↑

0.000

polymyxin B

0.5

99.5

3.1

96.9

0.7

99.3

↓

0.000

tigecycline

0

100

0

100

0

100

–

NA

K. pneumoniae

MDR

42.2

–

40.7

–

39.9

–

↑

0.000

ESBL-K. pneumoniae

28.7

–

27.8

–

27.6

–

↓

0.001

CR-K. pneumoniae

22.3

–

22.4

–

19.6

–

↑

0.000

amoxicillin/clavulanic acid

31.8

58.8

37.0

55.0

40.9

46.5

↑

0.000

piperacillin/tazobactam

25.8

70.6

17.5

70.2

26.2

65.2

↑

0.000

cefoperazone/sulbactam^a

27.5

67.6

27.3

66.4

26.3

69.5

↑

0.000

ceftazidime/avibactam

–

–

–

–

1.6

98.4

–

NA

cefazolin

48.5

47.6

44.7

52.1

42.4

54.3

–

0.723

cefuroxime

45.3

51.9

43.7

53.7

42.9

54.3

–

0.094

ceftazidime

34.8

62

32.9

62.9

32.5

64.9

↑

0.001

ceftriaxone

44.6

54.9

41.3

57.7

39.6

59.8

–

0.309

cefepime

33.4

58.4

32.0

61.9

25.1

66.0

–

0.03

cefoxitin

29.9

66.4

30.1

66.9

27.7

67.7

↑

0.004

moxalactam

21.1

76.4

20.4

76.4

18.9

79.5

↑

0.000

aztreonam

36.7

60.0

36.0

61.8

35.3

62.7

↑

0.000

ertapenem

–

–

22.2

77.1

19.6

79.5

–

0.115

imipenem

21.1

77.4

21.4

77.6

19.4

80.1

↑

0.000

meropenem

20.3

78.9

21.4

78.3

19.5

80.4

↑

0.000

amikacin

16.7

83.1

14.6

85.2

14.7

85.1

↑

0.000

gentamicin

31.6

67.1

27.7

71.7

26.8

72.6

–

0.036

ciprofloxacin

51.7

46.6

44.0

50.3

44.7

52.8

–

0.065

levofloxacin

39.5

51.0

34.9

53.9

35.7

55.5

↑

0.000

trimethoprim/sulfamethoxazole

44.6

55.4

36.3

63.7

37.0

63.0

–

0.147

fosfomycin

5.7

89.2

9.4

86.2

7.7

90.3

↑

0.000

polymyxin B

1.0

99.0

9.0

91.0

1.6

98.4

–

0.937

tigecycline

0

98.8

0.1

98.6

0.1

99.9

↓

0.001

E. cloacae

MDR

16.5

12.0

22.6

–

0.142

piperacillin/tazobactam

4.4

75.8

16.5

75.9

14.7

79.6

–

0.176

cefoperazone/sulbactam^a

4.4

79.1

10.8

82.9

10.6

81.9

–

0.868

ceftazidime/avibactam

–

–

–

–

6.0

94.0

–

NA

ceftazidime

33.0

62.6

27.2

70.3

32.5

64.9

–

0.229

ceftriaxone

44.0

56.0

32.9

66.5

38.5

60.4

–

0.039

cefepime

11.0

82.4

13.3

82.3

16.6

74.7

–

0.039

moxalactam

6.6

83.5

4.4

86.7

7.9

83.8

–

0.256

aztreonam

36.3

61.5

27.8

71.5

30.6

66.8

–

0.531

ertapenem

–

–

4.4

93.7

6.0

91.7

–

0.481

imipenem

6.6

93.4

4.4

92.4

5.3

94.3

–

0.437

meropenem

5.5

94.5

3.8

96.2

5.7

94.3

–

0.130

amikacin

2.2

96.7

0.6

99.4

2.3

97.4

–

0.262

gentamicin

14.3

79.1

11.4

87.3

18.1

78.9

–

0.156

ciprofloxacin

24.2

68.1

21.5

72.2

26.8

70.2

–

0.909

levofloxacin

17.6

75.8

17.7

77.2

15.5

73.2

–

0.125

trimethoprim/sulfamethoxazole

26.4

73.6

15.2

84.8

27.5

72.5

–

0.068

fosfomycin

0

96.7

2.5

94.3

1.5

94.0

–

0.084

polymyxin B

37.4

62.6

43.0

57.0

36.2

63.8

↑

0.000

tigecycline

0

98.9

0

96.2

0

99.6

↓

0.000

Klebsiella spp

MDR

11.9

14.9

11.5

↓

0.000

Piperacillin/tazobactam

15.3

76.3

21.6

63.5

20.0

74.6

–

0.266

Cefoperazone/Sulbactam^a

16.9

81.4

18.9

73.0

11.5

83.8

–

0.033

Ceftazidime/avibactam

–

–

–

–

4.6

95.4

–

NA

Cefazolin

41.9

38.7

40.6

37.5

30.5

42.4

↑

0.000

Cefuroxime

22.6

74.2

40.5

55.4

18.6

78.0

↓

0.000

Ceftazidime

22.0

72.9

37.8

62.2

24.6

73.1

–

0.445

Ceftriaxone

32.2

66.1

40.5

56.8

33.8

63.8

↓

0.000

Cefepime

10.2

88.1

20.3

77.0

9.2

85.4

↓

0.019

Cefoxitin

16.1

77.4

21.9

68.8

11.9

84.7

↓

0.000

Moxalactam

8.5

89.8

9.5

83.8

7.8

88.4

–

0.052

Aztreonam

22.0

74.6

31.1

66.2

25.4

73.1

↓

0.000

Ertapenem

–

–

10.8

82.4

5.4

93.1

↓

0.046

Imipenem

10.2

93.2

9.5

82.4

4.6

93.1

↑

0.004

Meropenem

5.1

96.6

10.8

87.8

3.8

96.2

↑

0.000

Amikacin

3.4

91.5

1.4

98.6

0.8

99.2

↓

0.000

Gentamicin

6.8

66.1

12.2

87.8

4.6

93.8

↑

0.000

Ciprofloxacin

28.8

76.3

25.7

68.9

17.7

81.5

↑

0.000

Levofloxacin

13.6

91.5

24.3

70.3

12.3

84.6

↑

0.000

Trimethoprim/Sulfamethoxazole

8.5

100

10.8

89.2

16.2

83.8

↓

0.000

Fosfomycin

0

84.7

5.4

89.2

3.1

95.4

↑

0.000

Polymyxin B

15.3

100

13.5

86.5

0.8

99.2

↑

0.000

Tigecycline

0

96.2

0

98.6

0

99.2

↓

0.000

Salmonella spp

MDR

63.0

–

35.7

–

52.1

–

↑

0.042

Amoxicillin

74.1

25.9

53.6

41.7

65.8

34.2

↑

0.000

Amoxicillin/Clavulanic Acid

9.3

38.9

8.1

61.9

6.0

47.9

–

0.943

Piperacillin/Tazobactam

0

98.1

2.4

88.1

0.9

99.1

–

0.128

Cefoperazone/Sulbactam^a

1.9

96.3

4.8

92.9

0

98.3

↓

0.000

Ceftazidime/Avibactam

–

–

–

0

100

–

NA

Ceftazidime

18.5

81.5

9.5

90.5

8.5

91.5

–

0.904

Ceftriaxone

22.2

77.8

10.7

89.3

8.5

91.5

–

0.833

Cefepime

13.0

77.8

4.8

92.9

5.1

94.0

↑

0.000

Moxalactam

1.9

87.0

2.4

96.4

0

99.1

–

0.079

Aztreonam

0

68.5

9.5

89.3

8.5

91.5

–

0.916

Ertapenem

–

–

1.2

98.8

0

100

–

0.156

Imipenem

0

98.1

1.2

98.8

0

100

–

0.059

Meropenem

1.0

87

1.2

98.8

0

100

↓

0.008

Amikacin

1.9

98.1

1.2

97.6

0.9

99.1

–

0.192

Gentamicin

7.4

87.0

4.8

95.2

10.3

89.7

–

0.236

Ciprofloxacin

22.2

22.2

19.0

31.0

12.0

35.0

–

0.193

Levofloxacin

3.7

61.1

8.3

23.8

15.4

28.2

↑

0.000

Trimethoprim/Sulfamethoxazole

20.4

79.6

14.3

85.7

15.4

84.6

–

0.091

Fosfomycin

0

100

1.2

98.8

0.9

98.3

↑

0.002

Polymyxin B

55.6

44.4

36.9

63.1

53.8

46.2

↑

0.000

Tigecycline

7.4

92.6

0

100

0

100

–

0.813

Serratia spp

MDR

12.8

–

5.8

–

5.9

–

↓

0.016

Piperacillin/Tazobactam

10.3

85.1

5.8

90.7

3.6

91.7

↓

0.000

Cefoperazone/Sulbactam^a

12.8

82.1

32.6

64.0

8.4

88.0

–

0.103

Ceftazidime/Avibactam

–

–

–

–

0

100

–

NA

Ceftazidime

10.3

88.1

1.2

96.5

15.9

84.1

↓

0.000

Ceftriaxone

33.3

74.6

37.2

62.8

19.3

80.7

↓

0.003

Cefepime

15.4

80.6

32.6

65.1

9.5

83.3

↓

0.043

Moxalactam

12.8

94.0

0

98.8

3.6

95.2

↓

0.001

Aztreonam

20.5

76.1

11.6

60.5

11.9

83.3

↓

0.000

Ertapenem

–

–

2.3

96.5

8.4

91.6

↑

0.015

Imipenem

17.9

94.0

2.3

88.4

8.3

90.5

↓

0.000

Meropenem

10.3

94.0

2.3

97.7

8.3

91.7

↓

0.000

Amikacin

5.1

97.0

0

100

1.2

98.8

↓

0.018

Gentamicin

28.2

79.1

29.1

70.9

7.1

92.9

↓

0.004

Ciprofloxacin

36.8

47.8

41.9

40.7

16.7

57.1

–

0.930

Levofloxacin

35.9

70.1

36.0

52.3

13.1

82.1

–

0.890

Trimethoprim/Sulfamethoxazole

10.3

88.1

1.2

98.8

0

100

↓

0.000

Fosfomycin

0

100

2.3

97.7

0

100

↑

0.020

Tigecycline

5.1

98.5

0

98.8

0

100

↓

0.000