Long-term care hospitals (N = 384) | Acute care hospitals (N = 185) | P-value | All hospitals (N = 569) | |
---|---|---|---|---|
Route of administration (%) | 0.562 | |||
Appropriate | 374 (97.4) | 182 (98.4) | 556 (97.7) | |
Inappropriate | 10 (2.6) | 3 (1.6) | 13 (2.3) | |
Dose (%) | < 0.001 | |||
Optimal | 112 (29.2) | 139 (75.1) | 251 (44.1) | |
Suboptimal: excessively high dose | 32 (8.3) | 2 (1.1) | 34 (6.0) | |
Inappropriate: excessively low dose | 62 (16.1) | 25 (13.5) | 87 (15.3) | |
N/A | 178 (46.4) | 19 (10.3) | 197 (34.6) | |
Antibiotic choice (%) | ||||
Antibiotics for the treatment of infectious diseases | 0.034 | |||
Optimal | 146/370 (39.5)1 | 82/155 (52.9) | 228/525 (43.4)1 | |
Suboptimal | 60/370 (16.2)1 | 16/155 (10.3) | 76/525 (14.5)1 | |
Inappropriate | 129/370 (34.9)1 | 44/155 (28.4) | 173/525 (33.0)1 | |
N/A | 35/370 (9.5)1 | 13/155 (8.4) | 48/525 (9.1)1 | |
Antibiotics for the prophylaxis of surgical site infection | 0.579 | |||
Appropriate | 1/3 (33.3) | 17/30 (56.7) | 18/33 (54.5) | |
Inappropriate | 2/3 (66.7) | 13/30 (43.3) | 15/33 (45.5) | |
Antibiotics for other or unknown reasons | – | |||
Appropriate | 0 | 0 | 0 | |
Inappropriate | 10/10 (100) | 10/10 (100) | 10/10 (100) | |
Appropriateness of antibiotic prescription, by each antibiotic (%) | < 0.001 | |||
Optimal | 49/384 (12.8) | 76/185 (41.1) | 125/569 (22.0) | |
Suboptimal | 29/384 (7.6) | 12/185 (6.5) | 41/569 (7.2) | |
Inappropriate | 109/384 (28.4) | 65/185 (35.1) | 174/569 (30.6) | |
N/A | 197/384 (51.3) | 32/185 (17.3) | 229/569 (40.2) | |
Appropriateness of antibiotic prescription, by each patient (%) | < 0.001 | |||
Optimal | 29/272 (10.7) | 57/150 (38.0) | 86/422 (20.4) | |
Suboptimal: one or more antibiotics were suboptimal | 26/272 (9.6) | 9/150 (6.0) | 35/422 (8.3) | |
Suboptimal: unnecessary combination therapy | 1/272 (0.4) | 4/150 (2.7) | 5/422 (1.2) | |
Inappropriate | 85/272 (31.3) | 50/150 (33.3) | 135/422 (32.0) | |
N/A | 131/272 (48.2) | 30/150 (20.0) | 161/422 (38.2) |