Table 2 Length of treatment (LOT) per indication
From: Detecting inappropriate total duration of antimicrobial therapy using semi-automated surveillance
Definitive diagnosis | Total (n) | Treatment courses with post-discharge treatment (n;%) | Percentage of total treatment duration given post-discharge (%;SD)* | LOT in days, (median; IQR) | Recommended course duration** | Guideline adherence*** (%) | Treatment courses too long (%) |
|---|---|---|---|---|---|---|---|
UTI—Cystitis | 420 | 231 (55) | 63 (21) | 6.5 (4.0–10.0) | 3–7 days | 53 | 31 |
UTI—Complicated UTI | 241 | 164 (68) | 63 (18) | 12.0 (7.0–15.0) | 7–14 days | 60 | 15 |
UTI—CAD | 28 | 15 (54) | 65 (18) | 11.0 (4.8–14.0) | 7–14 days | 57 | 14 |
UTI—Kidney transplant | 47 | 28 (60) | 59 (17) | 11.0 (5.5–15.0) | |||
UTI—Other (not specified) | 89 | 60 (67) | 68 (18) | 13.0 (7.0–15.0 | |||
RTI—CAP-m | 328 | 142 (43) | 54 (20) | 6.0 (5.0–8.0) | 5 days | 35 | 40 |
RTI—CAP-s | 90 | 17 (19) | 46 (24) | 5.0 (3.0–7.0) | 5 days | 29 | 31 |
RTI—HAP | 41 | 6 (15) | 37 (24) | 6.0 (4.0–8.0) | 5–7 days | 46 | 24 |
RTI—Aspiration | 82 | 23 (28) | 51 (20) | 6.5 (5.0–9.0) | 5 days | 26 | 50 |
RTI—COPD | 73 | 32 (44) | 58 (18) | 6.0 (3.0–8.0) | 7 days | 38 | 14 |
RTI—Abscess/empyema | 23 | 9 (39) | 55 (19) | 8.0 (5.5–15.0) | |||
RTI—Other (not specified) | 154 | 51 (33) | 56 (17) | 6.0 (3.0–8.8) | |||
CNS infection | 51 | 7 (14) | 70 (21) | 8.0 (3.0–11.5) | |||
CVL infection | 29 | 11 (38) | 59 (17) | 7.0 (4.0–13.0) | |||
ENT infection | 106 | 88 (83) | 63 (14) | 10.0 (9.0–13.0) | 7–14 days | 75 | 10 |
Gastro-enteritis | 40 | 14 (35) | 60 (21) | 5.0 (3.0–8.0) | |||
Gynaecological infection | 165 | 91 (55) | 68 (16) | 7.0 (2.0–11.0) | |||
Intra-abdominal infection | 464 | 145 (31) | 52 (19) | 6.0 (4.0–8.0) | |||
Sepsis e.c.i./unkown | 270 | 53 (20) | 56 (20) | 4.0 (3.0–7.0) | |||
Skin or soft tissue infection | 336 | 214 (64) | 62 (19) | 11.0 (7.0–15.0) | 10–14 days | 44 | 16 |
Other (not specified) | 157 | 49 (31) | 63 (19) | 6.0 (3.0–10.0) | |||
Total | 3390 | 1502 (44) | 60 (19) | 7.0 (4.0–11.0) | |||
Excluded**** | 232 |