Table 1 Baseline characteristics of 113 patients presenting methicillin-resistant Staphylococcus aureus bloodstream infections
Clinical characteristics | MSSA (N = 78) | MRSA (N = 35) | TOTAL (N = 113) | p value |
|---|---|---|---|---|
Gender, n (%) = male | 41 (52.6) | 19 (54.3) | 60 (53.1) | 1.00 |
Age (years), mean (range) | 58.4 (18–98) | 64.5 (39–87) | 62 (18–98) | 0.03 |
Underlying comorbidities, n (%) | ||||
Diabetes | 22 (28.2) | 11 (31.4) | 33 (29.2) | 0.83 |
Previous neutropenia | 2 (2.6) | 3 (8.6) | 5 (4.4) | 0.33 |
Acute renal insufficiency | 3 (3.8) | 3 (8.6) | 6 (5.3) | 0.38 |
End stage renal disease | 35 (44.9) | 8 (22.9) | 43 (38.0) | 0.16 |
Cardiopathy | 56 (71.8) | 21 (60.0) | 77 (68.1) | 0.62 |
Pneumopathy | 5 (6.4) | 7 (20.0) | 12 (10.6) | 0.10 |
Neurologic disease | 7 (8.9) | 2 (5.7) | 9 (8.0) | 0.72 |
Hepatopathy | 6 (7.7) | 6 (17.1) | 12 (10.6) | 0.20 |
Renal replacement therapy | 30 (38.5) | 8 (22.9) | 38 (33.6) | 0.30 |
Solid cancer | 12 (15.4) | 7 (20.0) | 19 (16.8) | 0.60 |
Hematologic cancer | 1 (1.3) | 4 (11.4) | 5 (4.4) | 0.04 |
Autoimmune disease | 1 (1.3) | 3 (8.6) | 4 (3.5) | 0.09 |
Solid organ transplant | 11 (14.1) | 3 (8.6) | 14 (12.4) | 0.55 |
Previous BSI | 11 (14.1) | 7 (20.0) | 18 (15.9) | 0.59 |
Acquisition, n (%) | ||||
HA-BSI | 35 (44.9) | 26 (74.6) | 61 (53.9) | 0.02 |
CA-BSI | 22 (28.2) | 5 (14.3) | 27 (23.9) | |
HCA-BSI | 21(26.9) | 4 (11.4) | 25 (22.1) | |
Infection source, n (%) | ||||
Central line vascular catheter | 42 (53.8) | 21 (60.0) | 63 (55.8) | 0.5 |
Pulmonary | 5 (6.4) | 1 (2.9) | 6 (5.3) | |
SSTI | 18 (23.1) | 10 (28.6) | 28 (24.8) | |
Primary bacteremia | 13 (16.7) | 3 (8.6) | 16 (14.2) | |
Outcome, n (%) | ||||
Death | 31 (39.7) | 19 (54.3) | 50 (44.2) | 0.15 |