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Table 6 Variables associated with final treatment failure in children

From: Success rates of MRSA decolonization and factors associated with failure

 

Total (n = 30)

Final treatment success (n = 13)

Final treatment failure (n = 17)

P-value univariable

Age, median

8.5

6

10

Not applicable

Gender, n (%)

Male

Female

14

16

6 (42.9)

7 (43.8)

8 (57.1)

9 (56.3)

1

Adopted and cleft lip/palate, n (%)

No

26

10 (38.5)

16 (61.5)

 

Yes

4

3 (75.0)

1 (25.0)

0.29

Pets

No

Yes

20

10

8 (40.0)

5 (50.0)

12 (60.0)

5 (50.0)

0.71

MRSA source, n (%)

Unknown a

3

5

2 (66.7)

3 (60.0)

1 (33.3)

2 (40.0)

Not applicable

Hospital-acquired

2

2 (100.0)

0 (0.0)

Livestock-associated

9

5 (55.6)

4 (44.4)

Community-acquired

Living in refugee centre

11

1 (9.1)

10 (90.9)

Comorbidity, n (%) b

No

Yes

18

12

8 (44.4)

5 (41.7)

10 (55.6)

7 (58.3)

1

Chronic pulmonary disease

Skin disease

Renal disease c

Devices d

2

4

4

6

1 (50.0)

1 (25.0)

3 (75.0)

2 (33.3)

1 (50.0)

3 (75.0)

1 (25.0)

7 (66.7)

 

AB use in the past 3 months, n (%) e

No

Yes

27

3

12 (44.4)

1 (33.3)

15 (55.6)

2 (66.7)

1

Hospital admission in the Netherlands in the past year, n (%) e

No

Yes

25

5

11 (44.0)

2 (40.0)

14 (56.0)

3 (60.0)

1

Skin lesions, n (%)

No

Yes

23

7

8 (34.8)

5 (71.4)

15 (65.2)

2 (28.6)

0.19

Travel abroad in the past year, n (%) e, f

No

Yes

18

12

10 (55.6)

3 (25.0)

8 (44.4)

9 (75.0)

0.14

Type of MRSA carriage, n (%)

Uncomplicated carriage

4

2 (50.0)

2 (50.0)

Not applicable

Complicated carriage

24

11 (45.8)

13 (54.2)

Infection & Complicated carriage

2

0

2 (100.0)

Location of MRSA carriage, n (%)

Nasal carriage

18

8 (44.4)

10 (55.6)

1

Non-nasal carriage

12

5 (41.7)

7 (58.3)

1

Throat carriage

23

9 (39.1)

14 (60.9)

0.67

Perineal carriage

9

5 (55.6)

4 (44.4)

0.44

Other sites

5

0 (0.0)

5 (100.0)

0.05

PVL positivity, n (%)

No

Yes

25

5

12 (48.0)

1 (20.0)

13 (52.0)

4 (80.0)

0.35

  1. aKnown risk factors are: previous MRSA carriage, contact with livestock, contact with MRSA positive person, hospital admission outside the Netherlands
  2. b The comorbidities mentioned below were merged together to get a larger sample size
  3. c Solid organ transplant (SOT) or dialysis
  4. d Tubing, catheters, probes, cannulas etc.
  5. e Measured counting from first visit infectious diseases consult
  6. f Travelling either to Asia, Africa, Central America or South America