Effect of temperature on Escherichia coli bloodstream infection in a nationwide population-based study of incidence and resistance

Table 4 Multivariable analysis of the effect of season and temperature on the incidence of bloodstream infection caused by E. coli with specific antibiotic-resistant profiles, by place of onset

Resistance phenotype	Variable	Community onset				Hospital onset
Resistance phenotype	Variable	Resistant/total tested	IRR	95% CI	P	Resistant/total tested	IRR	95% CI	P
Amoxicillin-clavulanic acid or ampicillin-sulbactam		1020/3009				445/963
	Holiday season		1.00	0.90, 1.11	> 0.9		1.07	0.87, 1.33	0.5
	Temperature, °C		1.01	1.00, 1.02	0.03		1.01	0.99, 1.03	0.4
3rd- or 4th-generation cephalosporins		964/3236				456/1003
	Holiday season		0.94	0.85, 1.05	0.30		0.96	0.78, 1.20	0.7
	Temperature, °C		1.01	1.00, 1.02	0.01		1.00	0.98, 1.02	0.8
Fluoroquinolones		1116/3266				495/1014
	Holiday season		0.97	0.88, 1.08	0.60		1.04	0.84, 1.28	0.7
	Temperature, °C		1.01	1.00, 1.02	0.02		1.00	0.98, 1.02	0.8

All models were adjusted for sex, age category and number of months since January 2018
Holiday season: July to October
IRR Incidence rate ratio, CI confidence interval

ISSN: 2047-2994