Table 2 Pooled prevalence of S. aureus resistance to different antibiotics in Nigeria
Antibiotics | No. of studies | Total No. of isolates | No. of resistant isolates | Pooled AMR prevalence (95% CI) | I2(P-value) (P ≤ 0.01) |
|---|---|---|---|---|---|
Vancomycin | 29 | 2546 | 340 | 0.13 (0.7, 0.21) | 96.60 |
Methicilin | 30 | 3109 | 1445 | 0.46 (0.37, 0.56) | 96.71 |
Ciprofloxacin | 44 | 2739 | 838 | 0.31 (0.24, 0.38) | 93.85 |
Tetracycline | 43 | 3359 | 2170 | 0.65 (0.56, 0.76) | 96.03 |
Cotrimoxazole | 21 | 1293 | 855 | 0.66 (0.55, 0.76) | 93.91 |
Chloramphenicol | 32 | 2015 | 943 | 0.47 (0.37, 0.56) | 95.03 |
Erythromycin | 66 | 4969 | 2325 | 0.47 (0.40, 0.53) | 95.31 |
Penicillin | 15 | 1709 | 1396 | 0.82 (0.61, 0.96) | 98.97 |
Clindamycin | 12 | 787 | 275 | 0.35 (0.23, 0.49) | 93.26 |
Amoxicillin | 40 | 2167 | 1614 | 0.74 (0.66, 0.81) | 94.64 |
Ampicillin | 28 | 2074 | 1408 | 0.68 (0.53, 0.81) | 97.91 |
Gentamycin | 77 | 5470 | 1701 | 0.31 (0.25, 0.37) | 95.90 |
Ceftriaxone | 25 | 2144 | 943 | 0.44 (0.34, 0.54) | 95.64 |
Amoxicillin/clavulanic acid | 20 | 1665 | 1032 | 0.62 (0.50, 0.73) | 95.76 |
Ceftazidim | 24 | 2179 | 1329 | 0.61 (0.46, 0.75) | 98.01 |
Cefuroxime | 17 | 1035 | 714 | 0.69 (0.51, 0.85) | 97.23 |
Cloxacillin | 22 | 1565 | 1205 | 0.77 (0.64, 0.88) | 97.13 |
Norfloxacillin | 9 | 491 | 162 | 0.33 (0.17, 0.52) | 95.27 |
Rifampicin | 7 | 302 | 72 | 0.24 (0.06, 0.48) | 95.19 |
Streptomycin | 20 | 1287 | 579 | 0.45 (0.34, 0.57) | 94.08 |
Ofloxacin | 25 | 2058 | 494 | 0.24 (0.18, 0.31) | 91.63 |
Trimethoprim | 6 | 291 | 160 | 0.55 (0.35, 0.74) | 91.99 |
Cefoxitine | 21 | 1791 | 770 | 0.43 (0.31, 0.56) | 96.61 |