From: First report of Candida auris in Romania: clinical and molecular aspects
Hospital 1 | Hospital 2 | Hospital 3 | Total | |
---|---|---|---|---|
Demographics | ||||
Mean age (years) | 66.5 | 50.8 | 65.3 | 63.3 |
Gender (% of men) | 100.00% | 60.00% | 81.80% | 80.00% |
Comorbidities | ||||
cardiovascular disease | 1 | 2 | 22 | 25 |
diabetes mellitus | 0 | 1 | 11 | 12 |
CKD | 0 | 2 | 4 | 6 |
liver disease | 0 | 0 | 4 | 4 |
malignancy | 1 | 0 | 2 | 3 |
chronic lung disease | 0 | 0 | 2 | 2 |
HIV | 0 | 0 | 2 | 2 |
Risk factors for C. auris presence | ||||
mean days before first isolation | 25.5 | 23.2 | 34.7 | 32.8 |
patients with prior ICU admission | 1 | 4 | 26 | 31 |
broad spectrum antibiotics before isolation | 2 | 5 | 33 | 40 |
antifungals before isolation | 1 | 2 | 24 | 27 |
COVID-19 | 1 | 0 | 8 | 9 |
Total patients with infection* | ||||
bloodstream infection | 0 | 4 | 11 | 15 |
urinary | 0 | 3 | 7 | 10 |
hospital-acquired pneumonia | 0 | 0 | 5 | 5 |
infected bedsore | 0 | 0 | 1 | 1 |
patients with multiple-site isolation | 0 | 3 | 3 | 6 |
Total patients with colonization | ||||
urine | 2 | 0 | 3 | 5 |
central line | 0 | 1 | 1 | 2 |
upper respiratory tract | 0 | 0 | 1 | 1 |
Undetermined | 0 | 0 | 7 | 7 |
upper respiratory tract | 0 | 0 | 5 | 5 |
urine | 0 | 0 | 2 | 2 |
All-cause mortality for infected patients | 0 | 1 (25%) | 17 (81%) | 18 (72%) |
All cause mortality for colonized patients | 1 (50%) | 1 (100%) | 2 (40%) | 4 (50%) |
All cause mortality for undetermined cases | 0 | 0 | 4 (57%) | 4 (57%) |
Total cases | 2 | 5 | 33 | 40 |