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Table 2 Univariate logistic regression for the association of suspected influence factors with SSIs and other HAIs

From: Antibiotic prophylaxis after 48 h postoperatively are not associated with decreased surgical site infections and other healthcare associated infections in pancreatic surgery patients: a retrospective cohort study

Exposure

SSIs

Other HAIs

OR (95% CI)

P value

OR (95% CI)

P value

Patient characteristics

    

Age (years)

1.01 (0.99, 1.02)

0.359

1.01 (0.99, 1.02)

0.448

Sex

    

 Male

1

 

1

 

 Female

0.53 (0.35, 0.80)

0.002

0.60 (0.38, 0.95)

0.031

Diabetes

    

 No

1

 

1

 

 Yes

0.96 (0.58, 1.60)

0.882

1.47 (0.87, 2.49)

0.149

Length of hospital stay

1.06 (1.05, 1.08)

< 0.001

1.07 (1.06, 1.09)

< 0.001

Surgical variables

    

Surgical category

    

 Pancreaticoduodenectomy

1

 

1

 

 Distal pancreatectomy

0.31 (0.18, 0.52)

< 0.001

0.28 (0.14, 0.54)

< 0.001

 Others

0.47 (0.26, 0.83)

0.009

1.03 (0.60, 1.76)

0.928

Surgical approach

    

 Non-endoscopic surgery

1

 

1

 

 Endoscopic surgery

0.57 (0.29, 1.12)

0.102

0.46 (0.20, 1.08)

0.073

Emergency

    

 No

1

 

1

 

 Yes

1.71 (0.84, 3.48)

0.137

1.31 (0.55, 3.15)

0.542

ASA score

    

 0

1

 

1

 

 1

1.73 (1.14, 2.63)

0.010

1.68 (1.04, 2.72)

0.033

NNIS score

    

 1 (0 and 1 point)

1

 

1

 

 2 (2 and 3 points)

2.04 (1.31, 3.19)

0.002

1.52 (0.89, 2.60)

0.126

Inpatient department

    

 Nonpancreatic center

1

 

1

 

 Pancreatic center

0.61 (0.34, 1.09)

0.097

0.80 (0.39, 1.65)

0.540

Surgeon

    

 Doctor 1

1

 

1

 

 Doctor 2

2.23 (0.82, 6.07)

0.118

3.27 (0.73, 14.69)

0.122

 Doctor 3

1.76 (0.68, 4.57)

0.243

2.85 (0.67, 12.14)

0.156

 Doctor 4

1.32 (0.41, 4.22)

0.644

4.42 (0.93, 20.86)

0.061

 Doctor 5

0.26 (0.03, 2.30)

0.226

3.70 (0.69, 19.87)

0.128

 Doctor 6

1.16 (0.39, 3.44)

0.784

3.04 (0.66, 13.99)

0.153

 Others

2.41 (0.83, 6.97)

0.105

3.52 (0.74, 16.82)

0.115

Surgical time (h)

1.40 (1.25, 1.57)

< 0.001

1.28 (1.13, 1.45)

< 0.001

Intraoperative blood loss (mL)

1.00 (1.00, 1.00)

0.029

1.00 (1.00, 1.00)

0.005

Antibiotic

    

Any AP

    

 No

1

 

1

 

 Yes

1.17 (0.65, 2.11)

0.591

0.48 (0.28, 0.82)

0.007

Intraoperative redosing

    

 Required but no redosing

1

 

1

 

 Required and redosing

2.32 (1.10, 4.91)

0.027

0.81 (0.24, 2.68)

0.725

 Not required

0.44 (0.26, 0.75)

0.002

0.63 (0.37, 1.09)

0.098

AP within 48 h postoperatively

    

 No

1

 

1

 

 Yes

1.94 (1.19, 3.16)

0.008

0.90 (0.45, 1.78)

0.759

AP days

1.07 (1.00, 1.15)

0.056

0.92 (0.81, 1.05)

0.236

  1. SSIs, surgical site infections; HAIs, healthcare-associated infections; OR, Odds ration; CI, confidence interval; ASA, American Society of Anesthesiology; NNIS, National Nosocomial Infections Surveillance; AP, antibiotic prophylaxis