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Table 1 Overview of included studies

From: Automated surveillance of non-ventilator-associated hospital-acquired pneumonia (nvHAP): a systematic literature review

References

Type of pneumonia

Year of surveillance

Country

Setting

Patient cohort to whom surveillance was applied

Number of patients (admissions) the Surveillance was Applied on

Patient cohort used for validation

Number of patients included for validation

Number of described surveillance systems

Type of surveillance system (fully automatic vs. semi-automatic)

Validation

Number of reference methods applied

Stern [22]

nvHAP

2015–2020

USA

152 hospitals

Hospitalized adult patients

3.1 Mio (2.7 Mioa

Random selection of patients meeting automated surveillance criteria for nvHAP

250 (215a)

1

Fully

Yes

6

Jones [25]

nvHAP

2015–2020 and 2018- 2020

USA

284 hospitals

Hospitalised adult patients

6.0 Mio

Random selection of patients meeting automated surveillance criteria for nvHAP

250

1

Fully

Yes

1

Valentine [28]

HAP

2015–2017 and 2020- 2021

Austra-lia

1 hospital

Hospitalised patients with (hemato-)oncologic disease

41′260

All patients meeting automated surveillance criteria for nvHAP

151

1

Fully

Yes

1

Ramirez Battle [24]

nvHAP

2015–2017

USA

1 hospital

Random selection of patients with ≥ 3 day stay and with worsening oxygenation

120

Random selection of patients with ≥ 3 day stay and with worsening oxygenation

120

1

Fully

Yes

3

Lacerna [10]

nvHAP

2012–2018

USA

21 hospitals

Hospitalized patients

Not reported

n.a

n.a

1

Fully

No

n.a

Ji [23]

nvHAP

2015–2018

USA

4 hospitals

Hospitalized non-ventilated patients aged 18 years or older

489′519

Random selection of patients with ≥ 3 day stay and with worsening oxygenation

120

10

Fully

Yes

1

Zilberberg [30]

HAP (gramnegative)

2009–2016

USA

178 institutions

Adult patients with positive microbiology culture

Not reported

n.a

n.a

1

Fully

No

n.a

Wolfensberger [21]

nvHAP

2016–2017

Switzer-land

1 hospital

Hospitalized adult patients

39′519

3 samples: 1. Random sample of all patients; 2. Patients with discharge diagnostic code of HAP; 3. Random sample plus patients with discharge code of HAP

700 + 637 + 754 = 2091

1

Semi

Yes

1

Wolfensberger [27]

HAP

2016

Switzer-land

4 departments in 1 hospital

Hospitalized patients from 3 surgical and 1 medical department

6064

All patients meeting automated surveillance criteria plus random sample of patients who did not meet automated surveillance criteria

165 + 590 = 755

1

Fully

Yes

1

Fitzhenry [31]

HAP (postoperative pneumonia)

1999–2006

USA

6 hospitals

Patients with surgical procedures (inpatient and outpatient)

Not reported for patients with inpatient surgical procedure exclusively

Patients with inpatient surgical procedure with in-hospital postoperative pneumonia based on VASQIP surveillance

1017

1

Fully

Yes

1

Bouzbid [29]

HAP on ICU

2000–2006

France

1 department in 1 hospital

Patients from 1 ICU with hospital stay > 48 h

1499

Patients from 1 ICU with hospital stay > 48 h

1499

6

Fully

Yes

1

Haas [19] and Mendonca [20].

HAP on Neo

2001–2003

USA

1 department in 1 hospital

Hospitalized patients from a neonatal intensive care unit (NICU)

1688 or 1692b

Hospitalized patients from a neonatal intensive care unit (NICU)

1688 or 1692b

1

Fully

Yes

1

  1. HAP, hospital-acquired pneumonia; ICU, intensive care unit; n.a., not applicable; Neo, neonatology; nvHAP, non-ventilator-associated hospital-acquired pneumonia; VASQIP, Veterans Affairs Surgical Quality Improvement Program
  2. aSubset of patients for validation against discharge diagnostic codes
  3. bDivergent numbers in papers of Haas et al. and Medonca et al