Barriers and facilitators to infection control at a hospital in northern India: a qualitative study
© The Author(s). 2017
Received: 20 December 2016
Accepted: 17 March 2017
Published: 8 April 2017
Hospital acquired infections occur at higher rates in low- and middle-income countries, like India, than in high-income countries. Effective implementation of infection control practices is crucial to reducing the transmission of hospital acquired infections at hospitals worldwide. Yet, no comprehensive assessments of the barriers to sustained, successful implementation of hospital interventions have been performed in Indian healthcare settings to date. The Systems Engineering Initiative for Patient Safety (SEIPS) model examines problems through the lens of interactions between people and systems. It is a natural fit for investigating the behavioral and systematic components of infection control practices.
We conducted a qualitative study to assess the facilitators and barriers to infection control practices at a 1250 bed tertiary care hospital in Haryana, northern India. Twenty semi-structured interviews of nurses and physicians, selected by convenience sampling, were conducted in English using an interview guide based on the SEIPS model. All interview data was subsequently transcribed and coded for themes.
Person, task, and organizational level factors were the primary barriers and facilitators to infection control at this hospital. Major barriers included a high rate of nursing staff turnover, time spent training new staff, limitations in language competency, and heavy clinical workloads. A well developed infection control team and an institutional climate that prioritizes infection control were major facilitators.
Institutional support is critical to the effective implementation of infection control practices. Prioritizing resources to recruit and retain trained, experienced nursing staff is also essential.
KeywordsInfection control Global health Qualitative methodology Human factors India
Healthcare associated infections (HAIs) affect millions of patients every year and are the most common complication of healthcare delivery globally . They complicate clinical care, increase length of hospital stays, and are particularly debilitating for patients and healthcare facilities with limited income and resources [2–4].
While HAIs are a considerable problem in high-income countries, low- and middle-income counties are disproportionately burdened by these infections [5, 6]. In India, a majority of healthcare settings lack robust infection control infrastructure and no nationwide HAI surveillance system exists . Low- and middle-income countries also tend to have higher rates of antimicrobial resistance . A recent multi-center study conducted at twelve Indian intensive care units found an overall rate of 9.06 HAIs per 1000 intensive care days, which is close to the global average in high income countries . However, there is considerable variability in infection rates at institutions across the country. Several single site studies have reported considerably higher HAI rates, with levels reaching between 25 and 40 infections per 1000 patient days [9–11].
Effective implementation of infection control practices is crucial to controlling the transmission of HAIs in settings with high infection rates. A recent meta-analysis found that over ninety-five percent intervention compliance is required to reduce central line-associated bloodstream infections . While the necessary rate of compliance is not known for other infections, all infection control interventions are complex, multifaceted, and challenging to sustain . In order for infection prevention measures to be successful, barriers to effective implementation must be identified and overcome . Likewise, facilitators to intervention implementation must also be identified and championed.
Despite the high rate of HAIs in India, no study of the comprehensive barriers and facilitators to infection control has been conducted at an Indian hospital, to our knowledge. Thus, we conducted a qualitative study of infection control practices at a tertiary care hospital in Haryana, northern India, based on the SEIPS conceptual framework.
We conducted a qualitative study of facilitators and barriers to infection control at a private tertiary care hospital in Haryana, India. Semi-structured interviews were conducted in June and July 2015.
Ten physicians and ten nurses were recruited at a 1250-bed tertiary care private hospital in Haryana, India. The hospital includes ten ICUs for a total of 350 ICU beds. Participants were selected by convenience sampling and represented a wide range of clinical departments and career levels. They were recruited in the hospital employee cafeteria, on clinical wards, and by word of mouth. To ensure a range of clinical expertise, some participants from less common sectors, for example infectious disease nursing and ICU leadership, were approached directly. All hospital employees directly involved in patient care were eligible for enrollment. Student trainees and non-English speakers were excluded, although no potential participants met exclusion criteria.
We conducted twenty semi-structured interviews to assess facilitators and barriers to a hospital infection control program. English language competency is a requirement for employment as a healthcare worker at the study hospital, thus, all interviews were conducted in English. Interviews took place at the hospital, in a room adjacent to the participant’s work environment. The initial interview guide was developed based on the SEIPS model (Fig. 1) and was refined during the study based on participant responses (Additional file 1). Interview questions assessed the hospital’s infection control policies, focusing on how people, physical environments, tasks, organizations, and tools are barriers and facilitators to the success of ongoing interventions. Most interviews lasted between ten and twenty minutes. All were audio recorded and transcribed for qualitative analysis.
Preliminary data analyses were conducted concurrently with study procedures to direct iterative revisions of the interview guide and determine theoretical saturation. Reworking the interview guide allowed the focus of the interview content to shift overtime, so that new information was gleaned even among later participants. After interviewing the twentieth participant, we decided that the responses to interview questions were becoming highly repetitive and that no new data were likely to appear. Thus, a twenty participant sample size was finalized based on theoretical saturation. Interview transcripts were subsequently analyzed using NVivo software (Version 11.3, QSR International), with responses coded for themes based on the SEIPS framework . NVivo is a qualitative software that aids data analysis by organizing the key themes that are identified by researchers in large quantities of open-ended text. Data were independently coded in NVivo by two investigators (AB and KB) who then jointly reviewed the analyses.
The institutional review board of the participating institution approved this study and the Health Sciences Institutional Review Board at the University of Wisconsin- Madison granted this study exemption from review. All participants provided oral consent before any data were collected.
Participants were comprised of ten nurses (80% female) and ten doctors (30% female), selected from a wide range of clinical departments including internal medicine, neurology, anesthesia, infectious disease, and three ICUs (cardiac, pediatric, and medicine). Three nurses were recruited from the hospital’s infection control department. Participants were enrolled from a range of career levels including junior and senior consulting physicians, residents, head nurses, and general nursing staff.
Tools and technology
Barriers and facilitators to infection control, categorized by components of the Systems Engineering Initiative for Patient Safety (SEIPS)
Tools and Technology
Clinician and visitors find mask uncomfortable
High nursing turnover
Shoe covers required in ICUs because of dust
New nurse hires often lack clinical experience
Heavy patient workload
No comprehensive electronic health record
Limited initial Hindi language capabilities
Ongoing construction within hospital
Frustration with the frequency of IC training
Ample IC supplies
Institutional climate that prioritizes IC
Centrally located sinks, hand gel at bedside
IC team well integrated into clinical care
Staff knowledgeable about IC practices
Electronic database for laboratory results
Funding and support for dedicated IC team
Sufficient beds to prevent overcrowding
Large environmental cleaning staff (600)
IC nurses help new hires complete IC tasks
Although the hospital’s health record was not fully electronic, an electronic microbial database served as the primary resource for treating physicians to access final laboratory results. Critical results were communicated from the microbiologist to the physician by phone and documented. Infection control nurses also utilized the electronic database for tracking patients, accessing microbiology results, and ensuring that correct contact precautions signage was promptly hung and precautions implemented.
Physicians identified nursing staff turnover as the single greatest barrier to infection control. This was also identified as a barrier by the infection control nurses, but not general nursing staff. Several participants reported high turnover rates, with nurses leaving primarily to take higher paying positions abroad. This was complicated by the fact that many new nurses entered directly from nursing school, without any prior work experience. “We have a huge turnover of nurses in our hospital. We lose around one-third of our intensive care staff every six months to the west or the Middle East.” -ICU, senior physician. While physicians knew that investing in the training of new nurses was crucial to patient care, it was also acknowledged to be time consuming and rarely resulted in long-term benefits for the healthcare team.
Participants also identified the limited Hindi language capabilities of incoming nurses as a considerable barrier to effective infection control. This was cited as a concern by general and infection control nurses, but no physicians. Hindi was the primary language used between healthcare workers when discussing clinical care. It is predominately spoken in northern India, but a majority of the nursing schools nationwide are located in the south. Thus, many nurses join the hospital with limited Hindi speaking abilities and initially struggle to communicate with patients and other staff. “There is a language barrier because a majority of nurses are from South India, but here (in Haryana), they use Hindi. […] In two or three months the nurses will pick up the language. Before, when I lived in southern India, I did not know Hindi. Now I do.” -Staff nurse.
Because most infection control training takes place in the first few months of employment, this is particularly hindered by limited language proficiency. “The nurses from Kerala [a southern state of India] do not know much Hindi or English, so sometimes we wonder how we should teach them to make them understand. […] There are so many things that are very difficult to teach them.” Infection control staff nurse. To help new nurses learn Hindi, head nurses often communicated with them in broken Hindi, even if they shared the same local language from the south.
Despite these barriers, the organization was committed to infection control and has facilitated it through the creation and staffing of a large infection control team. This includes sixteen nurses dedicated full-time to infection control activities. The hospital has also designated several physicians as leaders in ongoing infection control and antibiotic stewardship initiatives. These actions have created an institutional climate that prioritizes and values infection control. “Other institutions talk about infection control, but nobody emphasizes it like they are doing now. I have realized that this [hospital-acquired infections] is a major reason why my patients are staying in the hospital longer.”-Anesthesia, physician.
The hospital’s physical environment was structured and maintained to facilitate infection control. Each general ward had a centrally located sink with running water and alcohol based hand rub at the patients’ bedside. Rooms contained between one and six beds and patients under contact precautions were either placed into single rooms or cohorted. Overcrowding was not a problem and every patient was given their own bed. Each ICU had several sinks and a hand rub bottle for each patient.
Environmental cleaning was prioritized by the hospital, which employs more than six hundred cleaning staff on site. Housekeeping staff were recognized by study participants as key stakeholders in infection prevention. Anecdotally, they had the best hand hygiene compliance rates in the hospital and participants were adamant that environmental cleaning was comprehensive and timely. Staff decontaminated patient rooms three times a day, with common areas cleaned even more frequently. “Every two to three hours [housekeeping] will come.”-Cardiac ICU, senior staff nurse.
Sixteen nurses were dedicated to front-line implementation of hospital infection control policies. Each worked on specific units rounding with physicians, conducting daily hand hygiene and environmental cleaning audits, and providing new nurses with infection control training at the patient’s bedside. Because of the high rate of nursing turnover, these trainings occurred on a daily basis. “I am very strict and will say to them [the nurses] again and again, don’t do this or don’t do that. I instruct them, because I do not want my staff transmitting infections from one patient to another.” - Infection control staff nurse.
Infection control nurses were also responsible for ensuring that nursing staff completed infection control checklists for high risk patients at each shift. Most nurse and physician participants were receptive to the work of the infection control nurses. “If the nurse sees that someone is not doing it [hand hygiene], she will point it out, whether it is a doctor or a nurse. She’s like a police woman. […] We always do whatever she says, because even we forget that infection is such a problem in the ICUs. We have to take advice from her. We do not mind.” -ICU, senior physician. A few non-infection control nurses described frustration with the continual training and audits. “If it is a new person then it is fine, because they need training. But if you’ve been here for awhile, it is not so good.” -Staff nurse.
The typical nurse to patient ratio on the general wards was 1:6 and 1:1 or 1:2 in the ICU. Several non-infection control nurses expressed concern that they were understaffed and the daily workload was difficult to manage. “We are not getting any time to sit, or even to stand. We have to run just like in the Olympics.” -Pediatrics ICU, staff nurse.
The perceived workload had direct implications for infection control practices. Both staff nurses and infection control nurses reported that staff nurses were less likely to practice infection control properly when they were busy. “The knowledge is there, but some people are not implementing it [the practices…] If they are busy, sometimes they avoid it.” -Infection control nurse.
In this interview-based, qualitative analysis of the barriers and facilitators to infection control implementation in an Indian hospital, we found that staff turnover, time spent training new staff, limitations in language competency, and workload were major barriers to effective infection control. A well developed infection control team and an institutional climate that prioritizes infection control were major facilitators. Most of these barriers and facilitators mapped to the tasks, person, and organizational components of SEIPS.
These findings have implications for hospital leadership, infection control departments, and clinicians. It is especially imperative in resource constrained environments to implement interventions that are the most likely to be impactful. With the recognition of major barriers related to staffing, support from the highest levels of leadership is needed to implement policies that incentivize healthcare worker retention and recruitment. Hospital leadership must also prioritize the allocation of resources to rapidly build language and infection control skills for incoming healthcare workers. We recommend that hospitals incorporate intensive language training focused on medically relevant vocabulary into initial staff onboarding programs.
Two interventional studies from India also report on the role of person and organizational level factors in improving the implementation of infection control interventions. The first, assessing airborne infection control practices in thirty-five Indian healthcare settings, found that an intervention bundle focused on capacity building and systems development at the organizational level substantially improved the implementation of infection control policies . The second study introduced an organizational change process intervention known as appreciative inquiry to the maternity wards of three hospitals in Gujarat, India. Researchers found that the introduction of the appreciative inquiry program improved decision making and inter-personal relationships between healthcare workers, which in turn facilitated improved implementation and compliance of infection control practices . Furthermore, a recent international survey of infection prevention practices in thirty countries found that limited trained staff, infrastructure, and supplies were major barriers to preventing multidrug resistant organism transmission .
In our study, responses regarding the SEIPS factors physical environment and tools and technology primarily discussed facilitators to infection control. Participants reported an ample supply of gowns, masks, and gloves, placed in highly visible locations. Barriers to compliance centered around complex behavioral issues, instead of a lack of supplies. In contrast, a lack of personal protective equipment has previously been identified as a barrier to infection control in other Indian hospitals [21, 23]. These findings must be contextualized for the study institutions. One limitation of our study is that it focuses on a single tertiary care hospital that is internationally accredited by Joint Commission International. As such, our findings are likely not generalizable to India’s more resource limited healthcare settings.
Additional studies are needed from public government hospitals and other institution types. The Indian healthcare system is varied and complex with a high burden of antimicrobial resistance. Organized infection control programs are not routinely practiced, except in accredited healthcare organizations. Data regarding the barriers and facilitators from multiple types of healthcare settings are required to create a broader action plan of curbing antimicrobial resistance and healthcare associated infections.
Another limitation of the study is that we were not able to correlate self-reported practices with direct observations of infection control behavior. Future studies may identify additional barriers and facilitators of relevance by collecting such data via direct observation of hospital infection control practices.
Despite these limitations, we conducted, to our knowledge, the first SEIPS work system analysis of infection control practices at a hospital in India. Furthermore, our findings and methods provide institutions with an approach to identifying local barriers and facilitators to infection prevention that guide intervention implementation. Adaptation and tailoring interventions to local contexts is crucial. Designing solutions without identifying and accounting for such underlying inter-related barriers may lead to unsuccessful interventions and is a potential reason why interventions that have been successful in one setting may fail in another.
A work systems evaluation is a valuable exercise for organizations to identify new and evolving areas for improvement. At our Indian study hospital, tasks, person, and organizational level factors were key to the success of infection control practices. Institutional support for infection control and prioritizing resources to recruit and retain trained, experienced nursing staff are critical to the effective implementation of infection control practices.
Healthcare associated infections
Intensive care unit
Systems engineering initiative for patient safety
The research presented was supported by the Indo-US Science and Technology Forum S. N. Bose Scholars Program and a Graduate Student Award from the Global Health Institute at the University of Wisconsin, Madison. AB received funding as a pre-doctoral trainee under NIH award TL1TR000429 administered by the Clinical and Translational Science Award site funded by NIH award UL1TR000427. Content is the responsibility of the authors and does not necessarily represent the views of the funding agencies. These funding bodies had no role in the design of the study, data collection, data analysis, interpretation of data, writing of the manuscript, or the decision to submit the article for publication.
Availability of data and materials
De-identified interview transcripts are available on request from the corresponding author.
AB drafted and critically edited the manuscript, and contributed to study conception, design, data acquisition, and data analysis. KV and MA contributed to data collection, data analysis, and critical manuscript editing. DS drafted the discussion and edited the manuscript. SS and NS contributed to the study design and critical manuscript editing. All authors read and approved the final version of this manuscript.
The authors declare that they have no competing interests.
Consent for publication
Ethics approval and consent to participate
The Institutional Review Board at Medanta the Medicity Hospital approved this study and the Institutional Review Board at the University of Wisconsin granted this study exemption from review. All participants provided oral consent before any data were collected.
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
- World Health Organization. Patient Safety: Health care-associated infections [Internet]. WHO. 2014 [cited 2016 Dec 1]. Available from: http://www.who.int/gpsc/country_work/gpsc_ccisc_fact_sheet_en.pdf.
- Dubberke ER, Olsen MA. Burden of Clostridium difficile on the healthcare system. Clin Infect Dis. 2012;55(Suppl 2):S88–92.
- Lloyd-Smith P, Younger J, Lloyd-Smith E, Green H, Leung V, Romney MG. Economic analysis of vancomycin-resistant enterococci at a Canadian hospital: assessing attributable cost and length of stay. J Hosp Infect. 2013;85:54–9.View ArticlePubMedGoogle Scholar
- Perencevich EN, Stone PW, Wright SB, Carmeli Y, Fisman DN, Cosgrove SE, et al. Raising standards while watching the bottom line: making a business case for infection control. Infect Control Hosp Epidemiol. 2007;28:1121–33.View ArticlePubMedGoogle Scholar
- Allegranzi B, Bagheri Nejad S, Combescure C, Graafmans W, Attar H, Donaldson L, et al. Burden of endemic health-care-associated infection in developing countries: systematic review and meta-analysis. Lancet. 2011;377:228–41.View ArticlePubMedGoogle Scholar
- World Health Organization. The Burden of Health Care-Associated Infection Worldwide [Internet]. WHO. [cited 2016 Dec 3]. Available from: http://www.who.int/gpsc/country_work/summary_20100430_en.pdf.
- World Health Organization. Antimicrobial resistance: Global report on surveillance [Internet]. 2014. Available from: http://apps.who.int/iris/bitstream/10665/112642/1/9789241564748_eng.pdf.
- Mehta A, Rosenthal VD, Mehta Y, Chakravarthy M, Todi SK, Sen N, et al. Device-associated nosocomial infection rates in intensive care units of seven Indian cities. Findings of the International Nosocomial Infection Control Consortium (INICC). J Hosp Infect. 2007;67:168–74.View ArticlePubMedGoogle Scholar
- Kamat U, Ferreira A, Savio R, Motghare D. Antimicrobial resistance among nosocomial isolates in a teaching hospital in Goa. Indian J Community Med. 2008;33:89–92.View ArticlePubMedPubMed CentralGoogle Scholar
- Taneja N, Emmanuel R, Chari PS, Sharma M. A prospective study of hospital-acquired infections in burn patients at a tertiary care referral centre in North India. Burns. 2004;30:665–9.View ArticlePubMedGoogle Scholar
- Habibi S, Wig N, Agarwal S, Sharma S, Lodha R, Pandey R, et al. Epidemiology of nosocomial infections in medicine intensive care unit at a tertiary care hospital in northern India. Trop Doct. 2008;38:233–5.
- Furuya EY, Dick A, Perencevich EN, Pogorzelska M, Goldmann D, Stone PW. Central line bundle implementation in US intensive care units and impact on bloodstream infections. PLoS One. 2011;6:e15452.View ArticlePubMedPubMed CentralGoogle Scholar
- Whitby M, McLaws M-L, Slater K, Tong E, Johnson B. Three successful interventions in health care workers that improve compliance with hand hygiene: Is sustained replication possible? Am J Infect Control. 2008;36:349–55.View ArticlePubMedGoogle Scholar
- Anderson J, Gosbee LL, Bessesen M, Williams L. Using human factors engineering to improve the effectiveness of infection prevention and control. Crit Care Med. 2010;38:S269–281.View ArticlePubMedGoogle Scholar
- Carayon P, Hundt AS, Karsh B, Gurses AP, Alvarado CJ, Smith M, et al. Work system design for patient safety: the SEIPS model. Qual Saf Health Care. 2006;15:i50–8.View ArticlePubMedPubMed CentralGoogle Scholar
- Holden RJ, Carayon P, Gurses AP, Hoonakker P, Hundt AS, Ozok AA, et al. SEIPS 2.0: A human factors framework for studying and improving the work of healthcare professionals and patients. Ergonomics. 2013;56:1669–86.
- Yanke E, Zellmer C, Van Hoof S, Moriarty H, Carayon P, Safdar N. Understanding the current state of infection prevention to prevent clostridium difficile infection: a human factors and systems engineering approach. Am J Infect Control. 2015;43:241–7.View ArticlePubMedPubMed CentralGoogle Scholar
- Safdar N, Musuuza JS, Xie A, Hundt AS, Hall M, Wood K, et al. Management of ventilator-associated pneumonia in intensive care units: a mixed methods study assessing barriers and facilitators to guideline adherence. BMC Infect Dis. 2016;16:349.View ArticlePubMedPubMed CentralGoogle Scholar
- Caya T, Musuuza J, Yanke E, Schmitz M, Anderson B, Carayon P, et al. Using a systems engineering initiative for patient safety to evaluate a hospital-wide daily chlorhexidine bathing intervention. J Nurs Care Qual. 2015;30:337–44.View ArticlePubMedPubMed CentralGoogle Scholar
- Parmar MM, Sachdeva KS, Rade K, Ghedia M, Bansal A, Nagaraja SB, et al. Airborne infection control in India: baseline assessment of health facilities. Indian J Tuberc. 2015;62:211–7.View ArticlePubMedGoogle Scholar
- Sharma B, Ramani KV, Mavalankar D, Kanguru L, Hussein J. Using “appreciative inquiry” in India to improve infection control practices in maternity care: a qualitative study. Glob Health Action. 2015;8:26693.
- Safdar N, Sengupta S, Musuuza JS, Juthani-Mehta M, Drees M, Abbo LM, et al. Status of the Prevention of Multidrug-Resistant Organisms in International Settings: A Survey of the Society for Healthcare Epidemiology of America Research Network. Infect Control Hosp Epidemiol. 2016;38:53–60.
- Kotwal A, Taneja DK. Health care workers and universal precautions: perceptions and determinants of non-compliance. Indian J Community Med. 2010;35:526.View ArticlePubMedPubMed CentralGoogle Scholar