|
Bacterial species
|
MDRGNB culture positive groupa (n = 125)
|
MDRGNB culture negative groupb (n = 692)
|
|---|
|
Overall
|
Isolation site
|
Overall
|
Isolation site
|
|---|
|
Respiratoryc
|
Urine
|
Blood
|
Othersd
|
Respiratoryc
|
Urine
|
Blood
|
Othersd
|
|---|
|
Index hospitalizatione,f
|
|
Escherichia coli
|
47
|
(37.6)
|
17
|
(13.6)
|
26
|
(20.8)
|
4
|
(3.2)
|
7
|
(5.6)
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
|
Acinetobacter species
|
32
|
(25.6)
|
25
|
(20.0)
|
7
|
(5.6)
|
2
|
(1.6)
|
4
|
(3.2)
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
|
Pseudomonas aeruginosa
|
22
|
(17.6)
|
17
|
(13.6)
|
5
|
(4.0)
|
0
|
(0.0)
|
0
|
(0.0)
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
|
Klebsiella pneumoniae
|
21
|
(16.8)
|
15
|
(12.0)
|
6
|
(4.8)
|
1
|
(0.8)
|
1
|
(0.8)
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
|
Enterobacter species
|
17
|
(13.6)
|
11
|
(8.8)
|
5
|
(4.0)
|
1
|
(0.8)
|
3
|
(2.4)
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
|
Proteus mirabilis
|
4
|
(3.2)
|
3
|
(2.4)
|
1
|
(0.8)
|
0
|
(0.0)
|
0
|
(0.0)
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
|
Other bacteriag
|
20
|
(16.0)
|
13
|
(10.4)
|
2
|
(1.6)
|
3
|
(2.4)
|
2
|
(1.6)
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
–
|
|
Subsequent infectionf,h,i
|
|
Escherichia coli
|
24
|
(40.0)
|
9
|
(15.0)
|
13
|
(21.7)
|
3
|
(5.0)
|
1
|
(1.7)
|
13
|
(18.8)
|
2
|
(2.9)
|
8
|
(11.6)
|
3
|
(4.3)
|
2
|
(2.9)
|
|
Acinetobacter species
|
15
|
(25.0)
|
12
|
(20.0)
|
2
|
(3.3)
|
1
|
(1.7)
|
2
|
(3.3)
|
23
|
(33.3)
|
22
|
(31.9)
|
1
|
(1.4)
|
3
|
(4.3)
|
0
|
(0.0)
|
|
Pseudomonas aeruginosa
|
12
|
(20.0)
|
10
|
(16.7)
|
2
|
(3.3)
|
0
|
(0.0)
|
0
|
(0.0)
|
8
|
(11.6)
|
6
|
(8.7)
|
1
|
(1.4)
|
1
|
(1.4)
|
0
|
(0.0)
|
|
Klebsiella pneumoniae
|
10
|
(16.7)
|
6
|
(10.0)
|
4
|
(6.7)
|
0
|
(0.0)
|
0
|
(0.0)
|
14
|
(20.3)
|
9
|
(13.0)
|
2
|
(2.9)
|
3
|
(4.3)
|
1
|
(1.4)
|
|
Enterobacter species
|
1
|
(1.7)
|
0
|
(0.0)
|
0
|
(0.0)
|
1
|
(1.7)
|
0
|
(0.0)
|
7
|
(11.7)
|
7
|
(10.1)
|
0
|
(0.0)
|
0
|
(0.0)
|
0
|
(0.0)
|
|
Proteus mirabilis
|
5
|
(8.3)
|
3
|
(5.0)
|
0
|
(0.0)
|
0
|
(0.0)
|
2
|
(3.3)
|
3
|
(4.3)
|
1
|
(1.4)
|
0
|
(0.0)
|
0
|
(0.0)
|
1
|
(1.4)
|
|
Other bacteria
|
2
|
(3.3)j
|
0
|
(0.0)
|
2
|
(3.3)
|
0
|
(0.0)
|
0
|
(0.0)
|
5
|
(7.2)k
|
1
|
(1.4)
|
1
|
(1.4)
|
1
|
(1.4)
|
0
|
(0.0)
|
- aIndicates patients with at least 1 positive MDRGNB culture during index hospitalization
- bIndicates patients without any positive MDRGNB culture during index hospitalization
- cIncluding nasal swab, throat swab, and sputum culture
- dIncluding axillary or inguinal skin, wound, soft tissue pus, drainage, bile, pleural fluid, ascites, and catheter tip culture
- eIncluding surveillance and clinical culture during index hospitalization
- fOne MDR-GNB species could be isolated from different anatomical sites
- gIncluding Serratia marcescens (4), Morganella morganii (2), Achromobacter xylosoxidans (2), Burkholderia cepacia complex (1), Citrobacter freundii (3), Aeromonas hydrophila (1), Aeromonas sobria (1), Providencia stuartii (1), Sphingomonas paucimobilis (1), Klebsiella oxytoca (1), and unidentified nonfermentative gram-negative bacilli (3)
- hWithin 1 year after discharge from index hospitalization
- iDiagnosed with positive clinical culture and compatible clinical presentation
- jIncluding Serratia marcescens (1) and unidentified nonfermentative gram-negative bacilli (1)
- kIncluding Klebsiella oxytoca (2), Serratia marcescens (1), and unidentified non-fermentative gram-negative bacilli (2)
